Mitochondrial dysfunction drives persistent vascular fibrosis in rats after short-term exposure of PM2. 5

R Ning, Y Shi, J Jiang, S Liang, Q Xu, J Duan… - Science of The Total …, 2020 - Elsevier
Nowadays, the great majority of toxicological studies have focused on immediate
cardiovascular effects of simultaneous exposure to long-term or short-term PM 2.5; yet …

Association between very low-density lipoprotein cholesterol (VLDL-C) and carotid intima-media thickness in postmenopausal women without overt cardiovascular …

M Gentile, A Iannuzzi, F Giallauria, A D'Andrea… - Journal of Clinical …, 2020 - mdpi.com
Background: atherosclerotic process inexorably advances in patients reaching low-density
lipoprotein cholesterol (LDL-C) targets. An attractive hypothesis is that lipoprotein particles …

Increased backward wave pressures rather than flow explain age-dependent heart rate effects on central, but not peripheral arterial pressure

N Mthembu, GR Norton, VR Peterson, R Naran… - …, 2022 - Am Heart Assoc
Through both backward (Pb) and forward (Pf) wave effects, a lower heart rate (HR)
associates with increased central (PPc), beyond brachial pulse pressure (PP). However, the …

Preliminary study of carotid variables under ultrasound analysis as predictors for the risk of coronary arterial atherosclerosis

WB Cai, Y Wang, J Wang, WG Guo, YY Duan… - …, 2022 - Wiley Online Library
Background Carotid atherosclerosis by ultrasound scanning can be considered as an ideal
window to reflect systemic artery atherosclerosis, which has aroused wide concern for …

Impact of stroke work on the ability of left ventricular mass to account for pressure effects on function in a community with prevalent systemic flow-dependent …

H Bello, AJ Woodiwiss, R Naran… - Journal of …, 2021 - journals.lww.com
Aims: To determine whether the confounding influence of stroke work on left ventricular
mass (LVM) limits the ability of LVM to detect hypertensive LV dysfunction in systemic flow …

Proximal aortic stiffness modifies the relationship between heart rate and backward wave and hence central arterial pulse pressure

N Mthembu, VR Peterson, GR Norton… - Frontiers in …, 2022 - frontiersin.org
Aims A lower heart rate (HR) increases central blood pressure through enhanced backward
wave pressures (Pb). We aimed to determine whether these relationships are modified by …

Pulse wave velocity in South African women and children: comparison between the Mobil-O-Graph and SphygmoCor XCEL devices

A Kolkenbeck-Ruh, LM Soepnel, AW Kim… - Journal of …, 2022 - journals.lww.com
Background: Carotid-femoral pulse wave velocity (PWV) is the gold-standard noninvasive
measure of arterial stiffness. Data comparing tonometry-based devices such as the …

Relations of aortic stiffness with arterial damage beyond brachial pressure are both dependent and independent of central arterial pulsatile load

TH Motau, GR Norton, KN Mmopi, H Bello… - Journal of …, 2021 - journals.lww.com
Aim: We aimed to determine whether the impact of aortic stiffness on atherosclerotic or small
vessel end organ damage beyond brachial blood pressure depends in-part on stiffness …

[PDF][PDF] The Hypertensive Heart in Groups of African Ancestry in South Africa

H Bello - 2022 - wiredspace.wits.ac.za
Hypertensive heart failure is a major cause of death and disability in Africa and the world
today. Although much is known about the transition to heart failure in hypertension, there is …

[PDF][PDF] PREMATURE VASCULAR AGING IN PRECIPITOUS STROKE IN A MIDDLE-INCOME COUNTRY.

P Mabena - wiredspace.wits.ac.za
Stroke often occurs over a younger adult age range in low to middle-income countries. As
standard risk prediction strongly depends on age, the ability to detect the risk of stroke over …