Ion channels play a crucial role in a wide range of biological processes, including cell cycle
regulation and cancer progression. In particular, the transient receptor potential (TRP) family …

Transient receptor potential (TRP) channels are not only the major contributors to Ca2+
signaling but also the targets of Ca2+ signaling. Ca2+ regulation of TRP channels involves 3 …

Endothelial cells (ECs), as one of the most important types of vascular cells, line the
innermost layer of all blood vessels throughout human body and regulate vascular tone and …

Diabetes mellitus is one of the major risk factors for cardiovascular disease and is an
important health issue worldwide. Long-term diabetes causes endothelial dysfunction, which …

Vascular tone regulation is a key event in controlling blood flow in the body. Endothelial
cells (ECs) and vascular smooth muscle cells (VSMCs) help regulate the vascular tone …

A 24-h hypoxia exposure experiment was conducted to determine how hypoxia exposure
induce liver angiogenesis in largemouth bass. Nitrogen (N 2) was pumped into water to …

Background and Purpose In the acute phase of ischemia-reperfusion, hypoperfusion
associated with ischemia and reperfusion in microvascular regions and disruption of the …

Vascular endothelial cells regulate arterial tone through the release of nitric oxide and other
diffusible factors such as prostacyclin and endothelium derived hyperpolarizing factors …

Transient receptor potential vanilloid (TRPV) channels are TRP homologs and have been
classified into six subfamilies. They are unique mediators of sensory signals with multiple …

Transient receptor potential vanilloid 4 (TRPV4) is a non-selective cation channel that is
broadly expressed in different human tissues, including the digestive system, where it acts …