Autofluorescence‐based optical biopsy: An effective diagnostic tool in hepatology

AC Croce, A Ferrigno, G Bottiroli, M Vairetti - Liver International, 2018 - Wiley Online Library
Autofluorescence emission of liver tissue depends on the presence of endogenous
biomolecules able to fluoresce under suitable light excitation. Overall autofluorescence …

The role of tissue fluorescence in in vivo optical bioimaging

J Lifante, Y Shen, E Ximendes… - Journal of Applied …, 2020 - pubs.aip.org
The technological advancements made in optics and semiconductors (eg, cameras and
laser diodes) working with infrared have brought interest in optical bioimaging back to the …

Optimization of In vivo Imaging Provides a First Look at Mouse Model of Non-Alcoholic Fatty Liver Disease (NAFLD) Using Intravital Microscopy

RP Davis, BGJ Surewaard, M Turk, A Carestia… - Frontiers in …, 2020 - frontiersin.org
Non-alcoholic fatty liver disease is a spectrum of liver pathology ranging from simple
steatosis to steatohepatitis and can progress to diseases associated with poor outcomes …

Liver graft susceptibility during static cold storage and dynamic machine perfusion: DCD versus fatty livers

A Ferrigno, LG Di Pasqua, C Berardo… - International Journal of …, 2017 - mdpi.com
We compared static preservation (cold storage, CS, 4° C) with dynamic preservation
(machine perfusion, MP, 20° C) followed by reperfusion using marginal livers: a model of …

Deconvolution of the fluorescence spectra measured through a needle probe to assess the functional state of the liver

KY Kandurova, DS Sumin… - Lasers in Surgery …, 2023 - Wiley Online Library
Objectives Currently, one of the most pressing issues for surgeons in the treatment of
obstructive jaundice is the ability to assess the functional state of the liver and to detect and …

Spectrofluorometric analysis of autofluorescing components of crude serum from a rat liver model of ischemia and reperfusion

AC Croce, A Ferrigno, C Berardo, G Bottiroli, M Vairetti… - Molecules, 2020 - mdpi.com
Autofluorescence (AF) of crude serum was investigated with reference to the potential of its
intrinsic AF biomarkers for the noninvasive diagnosis of liver injury. Spectral parameters of …

[HTML][HTML] Fluorescence excitation properties of bilirubin in solution and in serum

AC Croce, A Ferrigno, G Bottiroli, LG Di Pasqua… - … of Photochemistry and …, 2021 - Elsevier
The bichromophore nature of bilirubin explains the presence of at least two partially
overlaying bands in both absorption and fluorescence emission spectra, and accounts for …

Fatty Acids and Bilirubin as Intrinsic Autofluorescence Serum Biomarkers of Drug Action in a Rat Model of Liver Ischemia and Reperfusion

AC Croce, A Ferrigno, G Palladini, B Mannucci… - Molecules, 2023 - mdpi.com
The autofluorescence of specific fatty acids, retinoids, and bilirubin in crude serum can
reflect changes in liver functional engagement in maintaining systemic metabolic …

[HTML][HTML] Lipids: Evergreen autofluorescent biomarkers for the liver functional profiling

AC Croce, G Bottiroli - European journal of histochemistry: EJH, 2017 - ncbi.nlm.nih.gov
Depending on their chemical nature, lipids can be classified in two main categories:
hydrophilic, greatly contributing to membrane composition and subcellular organelle …

Autofluorescence imaging within the liver: a promising tool for the detection and characterization of primary liver tumors

C Benoit, A Rodrigues, J Calderaro, C Charpy… - European …, 2022 - Springer
Objectives To assess the performance of 405 nm–induced autofluorescence for the
characterization of primary liver nodules on ex vivo resected specimens. Materials and …