When tissue antigens and antibodies get along: revisiting the technical aspects of immunohistochemistry—the red, brown, and blue technique

JA Ramos-Vara, MA Miller - Veterinary pathology, 2014 - journals.sagepub.com
Once focused mainly on the characterization of neoplasms, immunohistochemistry (IHC)
today is used in the investigation of a broad range of disease processes with applications in …

Technical aspects of immunohistochemistry

JA Ramos-Vara - Veterinary pathology, 2005 - journals.sagepub.com
Immunohistochemistry is an integral technique in many veterinary laboratories for diagnostic
and research purposes. In the last decade, the ability to detect antigens (Ags) in tissue …

Trends in 5-year survival rates among breast cancer patients by hormone receptor status and stage

L Chen, HM Linden, BO Anderson, CI Li - Breast cancer research and …, 2014 - Springer
Improvement in breast cancer survival has been observed in recent decades in the US, but it
is unclear if similar survival gains are consistent across breast cancer subtypes, especially …

Estrogen receptor analysis for breast cancer: current issues and keys to increasing testing accuracy

LK Diaz, N Sneige - Advances in anatomic pathology, 2005 - journals.lww.com
The estrogen receptor (ER) is a regulator of cellular growth, proliferation, and differentiation.
In addition to having prognostic value, ER is the most important biologic marker of …

Immunohistochemistry: fundamentals and applications in oncology

JA Ramos‐Vara, LB Borst - Tumors in domestic animals, 2016 - Wiley Online Library
In many laboratories, immunohistochemistry (IHC) has become a routine supplement to the
classic morphologic approach of investigational pathology. The specificity of the IHC test is …

[HTML][HTML] Immunohistochemistry for estrogen and progesterone receptors in the distinction of primary and metastatic mucinous tumors in the ovary: an analysis of 124 …

R Vang, AM Gown, TS Barry, DT Wheeler, BM Ronnett - Modern pathology, 2006 - Elsevier
Estrogen (ER) and progesterone receptor (PR) expression in primary ovarian mucinous
tumors and the utility of these markers for distinguishing metastatic mucinous carcinomas in …

Reliability of Her2/neu, estrogen receptor, and progesterone receptor testing by immunohistochemistry on cell block of FNA and serous effusions from patients with …

A Shabaik, G Lin, M Peterson, F Hasteh… - Diagnostic …, 2011 - Wiley Online Library
The prognostic and predictive value of Her2/neu and the hormone receptors in patient with
primary or metastatic breast cancer is essential for a favorable outcome of treatment. We …

Liquid-based cytology in fine-needle aspiration of breast lesions: a review

R Gerhard, FC Schmitt - Acta cytologica, 2014 - karger.com
Objective: Fine-needle aspiration (FNA) is a safe and cost-effective technique for the
diagnosis of breast lesions, especially when correlated with clinical and imaging studies …

Consistent immunostaining for cyclin D1 can be achieved on a routine basis using a newly available rabbit monoclonal antibody

W Cheuk, KOY Wong, CSC Wong… - The American journal of …, 2004 - journals.lww.com
Rabbit monoclonal antibody (MAb), which has become available only recently, theoretically
combines the advantage of the high affinity attributable to its rabbit origin and the high …

Systematic review on hormone receptor testing in breast cancer

S Nofech-Mozes, ET Vella, S Dhesy-Thind… - Applied …, 2012 - journals.lww.com
Assessment of hormone receptors (estrogen and progesterone) helps to direct therapy for
women with breast cancer. Immunohistochemistry is most commonly used to assess …