Breast cancer, the most frequent spontaneous malignancy diagnosed in women in the
western world, is continuously increasing in incidence in industrialized nations. Although …

The development of control-relevant models for a variety of biomedical engineering drug
delivery problems is reviewed in this paper. A summary of each control problem is followed …

Hayes' Principles and Methods of Toxicology has long been established as a reliable and
informative reference for the concepts, methodologies, and assessments integral to …

This practical guide presents a road map for safety assessment as an integral part of the
development of new drugs and therapeutics. Helps readers solve scientific, technical, and …

Continuing a long tradition, Lu's Basic Toxicology, Seventh Edition, combines relatively
comprehensive coverage of toxic substances in food, air, and water with brevity, thereby …

The source Dermal Absorption and Toxicity Assessment supplies a state-of-the-art overview
of the dermal absorption process, and is divided into six well organized sections. Written by …

Chloroform is a nongenotoxic-cytotoxic liver and kidney carcinogen and nasal toxicant in
some strains and sexes of rodents. Substantial evidence indicates that tumor induction is …

Pharmacokinetics (PK) involves the study of the rates of absorption, distribution, excretion,
and biotransformation of chemicals and their metabolites. PK models can be used to …

A method of generating a display, or representation, of a simulation model within a graphical
user interface (GUI) is described. The simulation model includes a number of objects, which …

In today's scientific and regulatory climates, an increased emphasis is placed on the
potential health impacts for children exposed either in utero or by nursing to drugs of abuse …