The emergence of modern photocatalysis, characterized by mildness and selectivity, has
significantly spurred innovative late-stage C–H functionalization approaches that make use …

Alkyl radicals are key intermediates in organic synthesis. Their classic generation from alkyl
halides has a severe drawback due to the employment of toxic tin hydrides to the point that …

Fluorinated pyrazoles play an important role in medicinal chemistry, drug discovery,
agrochemistry, coordination chemistry, and organometallic chemistry. Since the early 1990s …

Robotic systems for chemical synthesis are growing in popularity but can be difficult to run
and maintain because of the lack of a standard operating system or capacity for direct …

Herein, we report a method for C3-selective C–H tri-and difluoromethylthiolation of
pyridines. The method relies on borane-catalyzed pyridine hydroboration for generation of …

Selenium-based catalysts, due to their high efficiency, mild reaction conditions, good
functional compatibility and excellent selectivity, have attracted much attention during the …

A must-have resource for all the researchers working in the organofluorine and related fields
This timely two-volume set uniquely focuses on emerging fluorinated motifs beyond R-CF3 …

Recent protocols and reactions for catalytic radical perfluoroalkylations will be described.
The production of perfluoroalkyl radicals (RF= C n F2 n+ 1, n≥ 2), which effect both addition …

This review highlights the progress of aqueous fluoroalkylation over the past few decades.
Fluorine-containing functionalities are important design elements in new pharmaceuticals …

Due to their unique properties, fluorinated scaffolds are pivotal compounds in
pharmaceuticals, agrochemicals, and materials science. Over the last years, the …