Toxoplasma gondii is a ubiquitous parasitic protist found in a wide variety of hosts, including
a large proportion of the human population. Beyond an acute phase which is generally self …

One of the hallmarks of the parasitic phylum of Apicomplexa is the presence of highly
specialised, apical secretory organelles, called the micronemes and rhoptries that play …

Apicomplexan parasite growth and replication relies on nutrient acquisition from host cells,
in which intracellular multiplication occurs, yet the mechanisms that underlie the nutrient …

In living cells, microtubules (MTs) play pleiotropic roles, which require very different
mechanical properties. Unlike the dynamic MTs found in the cytoplasm of metazoan cells …

Protein kinases regulate fundamental aspects of eukaryotic cell biology, making them
attractive chemotherapeutic targets in parasites like Plasmodium spp. and Toxoplasma …

Sexual development in Toxoplasma gondii is a multistep process that culminates in the
production of oocysts, constituting approximately 50% of human infections. However, the …

Toxoplasmosis is a serious disease with global impact, now recognised as one of the most
important food borne diseases worldwide and a major cause of production loss in livestock …

Apicomplexan parasites cause persistent mortality and morbidity worldwide through
diseases including malaria, toxoplasmosis, and cryptosporidiosis. Ca 2+ signaling pathways …

Toxoplasma gondii possesses a limited set of actin-regulatory proteins and relies on only
three formins (FRMs) to nucleate and polymerize actin. We combined filamentous actin (F …

Human malaria, caused by infection with Plasmodium parasites, remains one of the most
important global public health problems, with the World Health Organization reporting more …