Abstract The Sustainable Development Goals (SDGs) and the Paris Agreement on Climate
Change call for deep transformations in every country that will require complementary …

Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer and a leading
cause of cancer-related deaths worldwide. Ninety percent of HCC cases arise from cirrhosis …

Background Despite compelling evidence on the health hazards of tobacco products
accumulated over the past 70 years, smoking remains a leading cause of death worldwide …

Background: Psoriasis is a common chronic inflammatory, debilitating, systemic disease with
great impact on healthcare systems worldwide. As targeted therapies have transformed the …

Background Neurological disorders are now the leading source of disability globally, and
ageing is increasing the burden of neurodegenerative disorders, including Parkinson's …

Summary Background The Global Burden of Diseases, Injuries, and Risk Factors Study
2017 (GBD 2017) includes a comprehensive assessment of incidence, prevalence, and …

Acute kidney injury (AKI) is a commonly encountered syndrome associated with various
aetiologies and pathophysiological processes leading to decreased kidney function. In …

Executive summary Pollution is the largest environmental cause of disease and premature
death in the world today. Diseases caused by pollution were responsible for an estimated 9 …

OBJECTIVE Despite the importance of diabetes for global health, the future economic
consequences of the disease remain opaque. We forecast the full global costs of diabetes in …

Background As mortality rates decline, life expectancy increases, and populations age, non-
fatal outcomes of diseases and injuries are becoming a larger component of the global …