Metabolomics in cancer research and emerging applications in clinical oncology

DR Schmidt, R Patel, DG Kirsch… - CA: a cancer journal …, 2021 - Wiley Online Library
Cancer has myriad effects on metabolism that include both rewiring of intracellular
metabolism to enable cancer cells to proliferate inappropriately and adapt to the tumor …

Ketogenic diet for human diseases: the underlying mechanisms and potential for clinical implementations

H Zhu, D Bi, Y Zhang, C Kong, J Du, X Wu… - Signal transduction and …, 2022 - nature.com
The ketogenic diet (KD) is a high-fat, adequate-protein, and very-low-carbohydrate diet
regimen that mimics the metabolism of the fasting state to induce the production of ketone …

A general overview on the hyperbaric oxygen therapy: applications, mechanisms and translational opportunities

MA Ortega, O Fraile-Martinez, C García-Montero… - Medicina, 2021 - mdpi.com
Hyperbaric oxygen therapy (HBOT) consists of using of pure oxygen at increased pressure
(in general, 2–3 atmospheres) leading to augmented oxygen levels in the blood …

Overcoming the blood–brain barrier for the therapy of malignant brain tumor: current status and prospects of drug delivery approaches

K Mitusova, OO Peltek, TE Karpov… - Journal of …, 2022 - Springer
Besides the broad development of nanotechnological approaches for cancer diagnosis and
therapy, currently, there is no significant progress in the treatment of different types of brain …

[HTML][HTML] Ketogenic diet in the treatment of cancer–where do we stand?

DD Weber, S Aminzadeh-Gohari, J Tulipan… - Molecular …, 2020 - Elsevier
Background Cancer is one of the greatest public health challenges worldwide, and we still
lack complementary approaches to significantly enhance the efficacy of standard anticancer …

ESPEN guidelines on nutrition in cancer patients

J Arends, P Bachmann, V Baracos, N Barthelemy… - Clinical nutrition, 2017 - Elsevier
Cancers are among the leading causes of morbidity and mortality worldwide, and the
number of new cases is expected to rise significantly over the next decades. At the same …

The potential health benefits of the ketogenic diet: a narrative review

K Dowis, S Banga - Nutrients, 2021 - mdpi.com
Considering the lack of a comprehensive, multi-faceted overview of the ketogenic diet (KD)
in relation to health issues, we compiled the evidence related to the use of the ketogenic diet …

Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders

K Augustin, A Khabbush, S Williams, S Eaton… - The Lancet …, 2018 - thelancet.com
High-fat, low-carbohydrate diets, known as ketogenic diets, have been used as a non-
pharmacological treatment for refractory epilepsy. A key mechanism of this treatment is …

3-hydroxybutyrate as a metabolite and a signal molecule regulating processes of living organisms

J Mierziak, M Burgberger, W Wojtasik - Biomolecules, 2021 - mdpi.com
3-hydroxybutyrate (3-HB) as a very important metabolite occurs in animals, bacteria and
plants. It is well known that in animals, 3-HB is formed as a product of the normal metabolism …

Redox regulation in cancer cells during metastasis

A Tasdogan, JM Ubellacker, SJ Morrison - Cancer discovery, 2021 - AACR
Metastasis is an inefficient process in which the vast majority of cancer cells are fated to die,
partly because they experience oxidative stress. Metastasizing cancer cells migrate through …