Imaging whole-brain activity to understand behaviour

A Lin, D Witvliet, L Hernandez-Nunez… - Nature Reviews …, 2022 - nature.com
Until now, most brain studies have focused on small numbers of neurons that interact in
limited circuits, allowing analysis of individual computations or steps of neural processing …

Radial glia in the zebrafish brain: Functional, structural, and physiological comparison with the mammalian glia

N Jurisch‐Yaksi, E Yaksi, C Kizil - Glia, 2020 - Wiley Online Library
The neuroscience community has witnessed a tremendous expansion of glia research. Glial
cells are now on center stage with leading roles in the development, maturation, and …

[HTML][HTML] Network statistics of the whole-brain connectome of Drosophila

A Lin, R Yang, S Dorkenwald, A Matsliah, AR Sterling… - Nature, 2024 - nature.com
Brains comprise complex networks of neurons and connections, similar to the nodes and
edges of artificial networks. Network analysis applied to the wiring diagrams of brains can …

Neural circuits for evidence accumulation and decision making in larval zebrafish

A Bahl, F Engert - Nature neuroscience, 2020 - nature.com
To make appropriate decisions, animals need to accumulate sensory evidence. Simple
integrator models can explain many aspects of such behavior, but how the underlying …

[HTML][HTML] Probabilistic models of larval zebrafish behavior reveal structure on many scales

RE Johnson, S Linderman, T Panier, CL Wee, E Song… - Current Biology, 2020 - cell.com
Nervous systems have evolved to combine environmental information with internal state to
select and generate adaptive behavioral sequences. To better understand these …

Thermoregulation in fish

M Haesemeyer - Molecular and Cellular Endocrinology, 2020 - Elsevier
Thermoregulation is critical for survival and animals therefore employ strategies to keep their
body temperature within a physiological range. As ectotherms, fish exclusively rely on …

Principles governing locomotion in vertebrates: lessons from zebrafish

EM Berg, ER Björnfors, I Pallucchi, LD Picton… - Frontiers in neural …, 2018 - frontiersin.org
Locomotor behaviors are critical for survival and enable animals to navigate their
environment, find food and evade predators. The circuits in the brain and spinal cord that …

Multiple convergent hypothalamus–brainstem circuits drive defensive behavior

M Lovett-Barron, R Chen, S Bradbury… - Nature …, 2020 - nature.com
The hypothalamus is composed of many neuropeptidergic cell populations and directs
multiple survival behaviors, including defensive responses to threats. However, the …

Real-time 3D movement correction for two-photon imaging in behaving animals

VA Griffiths, AM Valera, JYN Lau, H Roš, TJ Younts… - Nature …, 2020 - nature.com
Two-photon microscopy is widely used to investigate brain function across multiple spatial
scales. However, measurements of neural activity are compromised by brain movement in …

Ionotropic receptors specify the morphogenesis of phasic sensors controlling rapid thermal preference in Drosophila

G Budelli, L Ni, C Berciu, L van Giesen, ZA Knecht… - Neuron, 2019 - cell.com
Thermosensation is critical for avoiding thermal extremes and regulating body temperature.
While thermosensors activated by noxious temperatures respond to hot or cold, many …