Design of experiments (DoE) to develop and to optimize nanoparticles as drug delivery systems

MT Luiz, JSR Viegas, JP Abriata, F Viegas… - European Journal of …, 2021 - Elsevier
Nanotechnology has been widely applied to develop drug delivery systems to improve
therapeutic performance. The effectiveness of these systems is intrinsically related to their …

[HTML][HTML] Polymeric lipid hybrid nanoparticles (plns) as emerging drug delivery platform—A comprehensive review of their properties, preparation methods, and …

D Sivadasan, MH Sultan, O Madkhali, Y Almoshari… - Pharmaceutics, 2021 - mdpi.com
Polymeric lipid hybrid nanoparticles (PLNs) are core–shell nanoparticles made up of a
polymeric kernel and lipid/lipid–PEG shells that have the physical stability and …

Development of novel active packaging films based on whey protein isolate incorporated with chitosan nanofiber and nano-formulated cinnamon oil

M Mohammadi, S Mirabzadeh, R Shahvalizadeh… - International Journal of …, 2020 - Elsevier
Active packaging is designed to extend products shelf life by incorporating active
components with biological properties in its structure. The main goal of this research was to …

Nanostructured lipid carriers: versatile oral delivery vehicle

N Poonia, R Kharb, V Lather, D Pandita - Future science OA, 2016 - Taylor & Francis
Oral delivery is the most accepted and economical route for drug administration and leads to
substantial reduction in dosing frequency. However, this route still remains a challenge for …

Using the quality by design (QbD) approach to optimize formulations of lipid nanoparticles and nanoemulsions: A review

S Cunha, CP Costa, JN Moreira, JMS Lobo… - … , Biology and Medicine, 2020 - Elsevier
Abstract Quality-by-design (QbD) approach has been applied to optimize lipid-based
nanosystems formulations, including solid lipid nanoparticles (SLN), nanostructured lipid …

Encapsulation of Peppermint essential oil in nanostructured lipid carriers: In-vitro antibacterial activity and accelerative effect on infected wound healing

M Ghodrati, MR Farahpour, H Hamishehkar - Colloids and Surfaces A …, 2019 - Elsevier
Despite the use of essential oils for wound healing, their application is compromised due to
their hydrophobic and volatile nature. This study was conducted to evaluate the efficiency of …

Alginate hydrogel beads containing Thymus daenensis essential oils/Glycyrrhizic acid loaded in β-cyclodextrin. Investigation of structural, antioxidant/antimicrobial …

MA Shabkhiz, MK Pirouzifard, S Pirsa… - Journal of Molecular …, 2021 - Elsevier
In this study, glycyrrhizic acid (GA)(extracted from licorice root) and Thymus daenensis
essential oils (Td-EO) were loaded into ß-cyclodextrin (ß-CD) and subsequently, were co …

Efficacy of Mentha pulegium essential oil encapsulated into nanostructured lipid carriers as an in vitro antibacterial and infected wound healing agent

K Khezri, MR Farahpour, SM Rad - Colloids and Surfaces A …, 2020 - Elsevier
Nanostructured lipid carriers are used for protecting essential oils against environmental
factors and also for increasing antimicrobial capability. Gels prepared from Mentha pulegium …

Food grade nanostructured lipid carrier for cardamom essential oil: Preparation, characterization and antimicrobial activity

FK Nahr, B Ghanbarzadeh, H Hamishehkar… - Journal of functional …, 2018 - Elsevier
Cardamom essential oil (CEO) loaded food grade nanostructured lipid carriers (NLCs) were
produced using cocoa butter (as solid lipid) and Tween 80 (as surfactant) for application in …

Development and optimization of sulforaphane-loaded nanostructured lipid carriers by the Box-Behnken design for improved oral efficacy against cancer: In vitro, ex …

K Soni, MD Rizwanullah, K Kohli - Artificial cells, nanomedicine …, 2018 - Taylor & Francis
In the present study, sulforaphane (SFN)-loaded nanostructured lipid carriers (NLC) were
developed and optimized for improved oral efficacy against cancer. The SFN-loaded NLC …