The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia
Abstract The World Health Organization (WHO) classification of tumors of the hematopoietic
and lymphoid tissues was last updated in 2008. Since then, there have been numerous …
and lymphoid tissues was last updated in 2008. Since then, there have been numerous …
Ineffective erythropoiesis and its treatment
M Cazzola - Blood, The Journal of the American Society of …, 2022 - ashpublications.org
The erythroid marrow and circulating red blood cells (RBCs) are the key components of the
human erythron. Abnormalities of the erythron that are responsible for anemia can be …
human erythron. Abnormalities of the erythron that are responsible for anemia can be …
International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data
The classification of myeloid neoplasms and acute leukemias was last updated in 2016
within a collaboration between the World Health Organization (WHO), the Society for …
within a collaboration between the World Health Organization (WHO), the Society for …
Classification and personalized prognostic assessment on the basis of clinical and genomic features in myelodysplastic syndromes
M Bersanelli, E Travaglino, M Meggendorfer… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE Recurrently mutated genes and chromosomal abnormalities have been
identified in myelodysplastic syndromes (MDS). We aim to integrate these genomic features …
identified in myelodysplastic syndromes (MDS). We aim to integrate these genomic features …
Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes
DP Steensma, R Bejar, S Jaiswal… - Blood, The Journal …, 2015 - ashpublications.org
Recent genetic analyses of large populations have revealed that somatic mutations in
hematopoietic cells leading to clonal expansion are commonly acquired during human …
hematopoietic cells leading to clonal expansion are commonly acquired during human …
Clinical effect of driver mutations of JAK2, CALR, or MPL in primary myelofibrosis
E Rumi, D Pietra, C Pascutto… - Blood, The Journal …, 2014 - ashpublications.org
We studied the impact of driver mutations of JAK2, CALR,(calreticulin gene) or MPL on
clinical course, leukemic transformation, and survival of patients with primary myelofibrosis …
clinical course, leukemic transformation, and survival of patients with primary myelofibrosis …
Clinical effects of driver somatic mutations on the outcomes of patients with myelodysplastic syndromes treated with allogeneic hematopoietic stem-cell transplantation
MG Della Porta, A Gallì, A Bacigalupo… - Journal of clinical …, 2016 - ascopubs.org
Purpose The genetic basis of myelodysplastic syndromes (MDS) is heterogeneous, and
various combinations of somatic mutations are associated with different clinical phenotypes …
various combinations of somatic mutations are associated with different clinical phenotypes …
[HTML][HTML] Proposed minimal diagnostic criteria for myelodysplastic syndromes (MDS) and potential pre-MDS conditions
Myelodysplastic syndromes (MDS) comprise a heterogeneous group of myeloid neoplasms
characterized by peripheral cytopenia, dysplasia, and a variable clinical course with about …
characterized by peripheral cytopenia, dysplasia, and a variable clinical course with about …
[HTML][HTML] Proposed diagnostic criteria for classical chronic myelomonocytic leukemia (CMML), CMML variants and pre-CMML conditions
Chronic myelomonocytic leukemia (CMML) is a myeloid neoplasm characterized by
dysplasia, abnormal production and accumulation of monocytic cells and an elevated risk of …
dysplasia, abnormal production and accumulation of monocytic cells and an elevated risk of …
The International Consensus Classification of myelodysplastic syndromes and related entities
Abstract The International Consensus Classification (ICC) of myeloid neoplasms and acute
leukemia has updated the classification of myelodysplastic syndromes (MDSs) and placed …
leukemia has updated the classification of myelodysplastic syndromes (MDSs) and placed …