The cardiovascular system is subject to hyperlipidaemic, inflammatory, and pro-oxidant
stressors. Over time, these factors drive prevalent chronic diseases, of which atherosclerosis …

Immune mechanisms are critically involved in the pathogenesis of atherosclerosis and its
clinical manifestations. Associations of specific antibody levels and defined B-cell subsets …

IgA is produced in large quantities at mucosal surfaces by IgA+ plasma cells (PC), protecting
the host from pathogens, and restricting commensal access to the subepithelium. It is …

The sequestering of oxidation-modified low-density lipoprotein by macrophages results in
the accumulation of fatty deposits within the walls of arteries. Necrosis of these cells causes …

Introduction Chronic inflammatory diseases include cardiovascular disease (CVD),
atherosclerosis, rheumatic and autoimmune diseases, and others, constituting a large part of …

A large body of literature has established the link between periodontal disease and
cardiovascular disease. Oxidized low-density lipoproteins (OxLDLs) have a crucial role in …

Atherosclerosis is a lipid-driven chronic inflammatory disease that is modulated by innate
and adaptive immunity including humoral immunity. Importantly, antibody alterations …

We previously demonstrated that the dendritic cell (DC)-targeting nasal double DNA
adjuvant system, which consists of a DNA plasmid expressing Flt3 ligand (pFL) and CpG …

Purpose Inflammation is implicated in cardiovascular disease (CVD), but the association of
total serum immunoglobulin (Ig) A, G, and M with CVD across the whole spectrum of …

Obesity is associated with low‐grade inflammation and increased systemic oxidative stress.
Roux‐en‐Y gastric bypass (RYGB) surgery is known to ameliorate the obesity‐induced …