The role of B cells in atherosclerosis
AP Sage, D Tsiantoulas, CJ Binder… - Nature Reviews Cardiology, 2019 - nature.com
The cardiovascular system is subject to hyperlipidaemic, inflammatory, and pro-oxidant
stressors. Over time, these factors drive prevalent chronic diseases, of which atherosclerosis …
stressors. Over time, these factors drive prevalent chronic diseases, of which atherosclerosis …
Humoral immunity in atherosclerosis and myocardial infarction: from B cells to antibodies
Immune mechanisms are critically involved in the pathogenesis of atherosclerosis and its
clinical manifestations. Associations of specific antibody levels and defined B-cell subsets …
clinical manifestations. Associations of specific antibody levels and defined B-cell subsets …
Fantastic IgA plasma cells and where to find them
B Isho, A Florescu, AA Wang… - Immunological …, 2021 - Wiley Online Library
IgA is produced in large quantities at mucosal surfaces by IgA+ plasma cells (PC), protecting
the host from pathogens, and restricting commensal access to the subepithelium. It is …
the host from pathogens, and restricting commensal access to the subepithelium. It is …
Antibodies in action: the role of humoral immunity in the fight against atherosclerosis
JA Taylor, MA Hutchinson, PJ Gearhart, RW Maul - Immunity & Ageing, 2022 - Springer
The sequestering of oxidation-modified low-density lipoprotein by macrophages results in
the accumulation of fatty deposits within the walls of arteries. Necrosis of these cells causes …
the accumulation of fatty deposits within the walls of arteries. Necrosis of these cells causes …
Antibodies against phosphorylcholine and protection against atherosclerosis, cardiovascular disease and chronic inflammation
J Frostegård - Expert Review of Clinical Immunology, 2022 - Taylor & Francis
Introduction Chronic inflammatory diseases include cardiovascular disease (CVD),
atherosclerosis, rheumatic and autoimmune diseases, and others, constituting a large part of …
atherosclerosis, rheumatic and autoimmune diseases, and others, constituting a large part of …
Salivary IgA to MAA-LDL and oral pathogens are linked to coronary disease
A large body of literature has established the link between periodontal disease and
cardiovascular disease. Oxidized low-density lipoproteins (OxLDLs) have a crucial role in …
cardiovascular disease. Oxidized low-density lipoproteins (OxLDLs) have a crucial role in …
Role of Antibodies and Their Specificities in Atherosclerotic Cardiovascular Disease
J Deroissart, CJ Binder, F Porsch - … , Thrombosis, and Vascular …, 2024 - ahajournals.org
Atherosclerosis is a lipid-driven chronic inflammatory disease that is modulated by innate
and adaptive immunity including humoral immunity. Importantly, antibody alterations …
and adaptive immunity including humoral immunity. Importantly, antibody alterations …
A nasal double DNA adjuvant system induces atheroprotective IgM antibodies via dendritic cell-B-1a B cell interactions
H Yoshimatsu, K Kataoka, K Fujihashi, T Miyake, Y Ono - Vaccine, 2022 - Elsevier
We previously demonstrated that the dendritic cell (DC)-targeting nasal double DNA
adjuvant system, which consists of a DNA plasmid expressing Flt3 ligand (pFL) and CpG …
adjuvant system, which consists of a DNA plasmid expressing Flt3 ligand (pFL) and CpG …
The association of serum immunoglobulins with risk of cardiovascular disease and mortality: the Rotterdam Study
SR Khan, VASH Dalm, MK Ikram, RP Peeters… - Journal of Clinical …, 2023 - Springer
Purpose Inflammation is implicated in cardiovascular disease (CVD), but the association of
total serum immunoglobulin (Ig) A, G, and M with CVD across the whole spectrum of …
total serum immunoglobulin (Ig) A, G, and M with CVD across the whole spectrum of …
Total fecal IgA levels increase and natural IgM antibodies decrease after gastric bypass surgery
N Istomin, MA Härma, R Akhi, AE Nissinen… - Apmis, 2022 - Wiley Online Library
Obesity is associated with low‐grade inflammation and increased systemic oxidative stress.
Roux‐en‐Y gastric bypass (RYGB) surgery is known to ameliorate the obesity‐induced …
Roux‐en‐Y gastric bypass (RYGB) surgery is known to ameliorate the obesity‐induced …