ABSTRACT DNA methylation is an epigenetic modification critical to normal genome
regulation and development. The vitamin folate is a key source of the one carbon group …

Cancer-associated DNA hypomethylation is as prevalent as cancer-linked hypermethylation,
but these two types of epigenetic abnormalities usually seem to affect different DNA …

A wide range of cytotoxic and mutagenic DNA bases are removed by different DNA
glycosylases, which initiate the base excision repair pathway. DNA glycosylases cleave the …

The genome is programmed by the epigenome. Two of the fundamental components of the
epigenome are chromatin structure and covalent modification of the DNA molecule itself by …

▪ Abstract The past few years have seen a wider acceptance of a role for DNA methylation in
cancer. This can be attributed to three developments. First, the documentation of the over …

Glucocorticoid hormones were found to regulate DNA demethylation within a key enhancer
of the rat liver‐specific tyrosine aminotransferase (Tat) gene. Genomic footprinting analysis …

Genomic imprinting occurs in both male and female gametes during gametogenesis, but the
exact time when imprinting begins and ends is unknown. In the present study we injected …

DNA methylation is an epigenetic process involved in embryonic development,
differentiation and aging. It is 1 of the mechanisms resulting in gene silencing in …

The putative de novo methyltransferases, Dnmt3a and Dnmt3b, were reported to have weak
methyltransferase activity in methylating the 3′ long terminal repeat of Moloney murine …

Context: Endometriosis is an estrogen-dependent disease. Steroidogenic factor-1 (SF-1), a
transcriptional factor essential for activation of multiple steroidogenic genes for estrogen …