[HTML][HTML] Recent Advances in Ocular Drug Delivery: Insights into Lyotropic Liquid Crystals

S Adwan, M Qasmieh, F Al-Akayleh, ASA Ali Agha - Pharmaceuticals, 2024 - mdpi.com
Background/Objectives: This review examines the evolution of lyotropic liquid crystals
(LLCs) in ocular drug delivery, focusing on their ability to address the challenges associated …

Novel therapeutic deep eutectic system for the enhancement of ketoconazole antifungal activity and transdermal permeability

F Al-Akayleh, B Alkhawaja, N Al-Zoubi… - Journal of Molecular …, 2024 - Elsevier
In this study, we reported the investigation of a novel therapeutic deep eutectic system
(THEDES) formed between capric acid (CA) and ketoconazole (KCZ) to enhance the …

[HTML][HTML] Antioxidant activity and UHPLC-MS/MS characterization of polyphenol and nicotine content in Nicotiana glauca leaf extracts: a comparative study of …

R Issa, F Al-Akayleh, L Alnsour, TR Al-Sammarraie… - Plants, 2024 - mdpi.com
The leaves of Nicotiana glauca (N. glauca; Solanaceae) plant are a known, major human
health concern. This study investigated the antioxidant activity and polyphenols composition …

Deep Eutectic System-Based Liquisolid Nanoparticles as Drug Delivery System of Curcumin for In-Vitro Colon Cancer Cells

A Nakaweh, F Al-Akayleh, M Al-Remawi… - Journal of …, 2024 - Springer
Purpose This study aims to improve curcumin's solubility and anti-cancer effectiveness by
utilizing deep eutectic solvents (DES)-based liquisolid nanoparticles. This study aims to …

Eutectic-based self-emulsifying drug delivery system for enhanced oral delivery of risperidone

A Rifai, B Alkhawaja, F Al-Akayleh… - Journal of Dispersion …, 2024 - Taylor & Francis
Implementing therapeutic deep eutectic systems (THDESs) in various drug delivery systems
(DDSs) has expanded enormously. THDESs offer eco-friendly alternatives to conventional …

An Investigation into the Preparation, Characterization, and Therapeutic Applications of Novel Gefitinib/Capric Acid Deep Eutectic Systems

F Al-Akayleh, B Alkhawaja, M Al-Remawi… - Journal of …, 2024 - Springer
Purpose In this work, we sought to report and fully characterise novel therapeutic deep
eutectic systems (THEDESs) formed between Gefitinib (Gef) and capric acid (CA). In …

Testing the prediction capability of trained models: sildenafil citrate solubility in propylene glycol and 1-propanol mixtures at different temperatures

A Jouyban, F Martinez, H Rezaei - Physics and Chemistry of …, 2024 - Taylor & Francis
This study investigates the thermodynamic characteristics, equilibrium solubility, and
solvation dynamics of sildenafil citrate within binary solvent systems composed of propylene …