MSCs: delivery routes and engraftment, cell‐targeting strategies, and immune modulation

TJ Kean, P Lin, AI Caplan, JE Dennis - Stem cells international, 2013 - Wiley Online Library
Mesenchymal stem cells (MSCs) are currently being widely investigated both in the lab and
in clinical trials for multiple disease states. The differentiation, trophic, and …

Mesenchymal stem/stromal cells as a pharmacological and therapeutic approach to accelerate angiogenesis

A Bronckaers, P Hilkens, W Martens, P Gervois… - Pharmacology & …, 2014 - Elsevier
Mesenchymal stem cells or multipotent stromal cells (MSCs) have initially captured attention
in the scientific world because of their differentiation potential into osteoblasts …

Exosomes derived from atorvastatin-pretreated MSC accelerate diabetic wound repair by enhancing angiogenesis via AKT/eNOS pathway

M Yu, W Liu, J Li, J Lu, H Lu, W Jia, F Liu - Stem cell research & therapy, 2020 - Springer
Background Mesenchymal stem cell (MSC)-derived exosomes emerge as promising
candidates for treating delayed wound healing in diabetes due to the promotion of …

Wound dressings composed of copper-doped borate bioactive glass microfibers stimulate angiogenesis and heal full-thickness skin defects in a rodent model

S Zhao, L Li, H Wang, Y Zhang, X Cheng, N Zhou… - Biomaterials, 2015 - Elsevier
There is a need for better wound dressings that possess the requisite angiogenic capacity
for rapid in situ healing of full-thickness skin wounds. Borate bioactive glass microfibers are …

Preparation of copper-containing bioactive glass/eggshell membrane nanocomposites for improving angiogenesis, antibacterial activity and wound healing

J Li, D Zhai, F Lv, Q Yu, H Ma, J Yin, Z Yi, M Liu… - Acta biomaterialia, 2016 - Elsevier
Effectively stimulating angiogenesis and avoiding wound infection are great challenges in
wound care management. Designing new healing dressings with requisite angiogenic …

Injectable, self-healing and pH responsive stem cell factor loaded collagen hydrogel as a dynamic bioadhesive dressing for diabetic wound repair

L Zhang, Y Zhou, D Su, S Wu, J Zhou… - Journal of Materials …, 2021 - pubs.rsc.org
As one of the serious complications of diabetes, diabetic ulcers induce several clinical
problems. Although a variety of wound dressings are commonly employed, their role is too …

Diminazene attenuates pulmonary hypertension and improves angiogenic progenitor cell functions in experimental models

V Shenoy, A Gjymishka, YP Jarajapu, Y Qi… - American journal of …, 2013 - atsjournals.org
Rationale: Studies have demonstrated that angiotensin-converting enzyme 2 (ACE2) plays a
protective role against lung diseases, including pulmonary hypertension (PH). Recently, an …

Liraglutide-loaded PLGA/gelatin electrospun nanofibrous mats promote angiogenesis to accelerate diabetic wound healing via the modulation of miR-29b-3p

M Yu, J Huang, T Zhu, J Lu, J Liu, X Li, X Yan… - Biomaterials …, 2020 - pubs.rsc.org
Diabetic wounds remain a serious clinical challenge whereas current therapies have limited
effects on reducing the high disability and morbidity. Impaired vascularization is closely …

Silk biomaterials with vascularization capacity

H Han, H Ning, S Liu, Q Lu, Z Fan, H Lu… - Advanced functional …, 2016 - Wiley Online Library
Functional vascularization is critical for the clinical regeneration of complex tissues such as
kidney, liver, or bone. The immobilization or delivery of growth factors has been explored to …

The healing of full-thickness burns treated by using plasmid DNA encoding VEGF-165 activated collagen–chitosan dermal equivalents

R Guo, S Xu, L Ma, A Huang, C Gao - Biomaterials, 2011 - Elsevier
Repair of deep burn by use of the dermal equivalent relies strongly on the angiogenesis and
thereby the regeneration of dermis. To enhance the dermal regeneration, in this study …