Traumatic brain injuries: pathophysiology and potential therapeutic targets
SY Ng, AYW Lee - Frontiers in cellular neuroscience, 2019 - frontiersin.org
Traumatic brain injury (TBI) remains one of the leading causes of morbidity and mortality
amongst civilians and military personnel globally. Despite advances in our knowledge of the …
amongst civilians and military personnel globally. Despite advances in our knowledge of the …
Early management of severe traumatic brain injury
Severe traumatic brain injury remains a major health-care problem worldwide. Although
major progress has been made in understanding of the pathophysiology of this injury, this …
major progress has been made in understanding of the pathophysiology of this injury, this …
Effect of exosomes derived from multipluripotent mesenchymal stromal cells on functional recovery and neurovascular plasticity in rats after traumatic brain injury
OBJECT Transplanted multipotent mesenchymal stromal cells (MSCs) improve functional
recovery in rats after traumatic brain injury (TBI). In this study the authors tested a novel …
recovery in rats after traumatic brain injury (TBI). In this study the authors tested a novel …
Systemic administration of cell-free exosomes generated by human bone marrow derived mesenchymal stem cells cultured under 2D and 3D conditions improves …
Y Zhang, M Chopp, ZG Zhang, M Katakowski… - Neurochemistry …, 2017 - Elsevier
Multipotent human bone marrow derived mesenchymal stem cells (hMSCs) improve
functional outcome after experimental traumatic brain injury (TBI). The present study was …
functional outcome after experimental traumatic brain injury (TBI). The present study was …
Exosomes derived from bone mesenchymal stem cells ameliorate early inflammatory responses following traumatic brain injury
Traumatic brain injury (TBI) is a leading cause of mortality and disability worldwide. Although
treatment guidelines have been developed, no best treatment option or medicine for this …
treatment guidelines have been developed, no best treatment option or medicine for this …
The contribution of gliosis to diffusion tensor anisotropy and tractography following traumatic brain injury: validation in the rat using Fourier analysis of stained tissue …
Diffusion tensor imaging is highly sensitive to the microstructural integrity of the brain and
has uncovered significant abnormalities following traumatic brain injury not appreciated …
has uncovered significant abnormalities following traumatic brain injury not appreciated …
MSCs-derived exosomes and neuroinflammation, neurogenesis and therapy of traumatic brain injury
Y Yang, Y Ye, X Su, J He, W Bai, X He - Frontiers in cellular …, 2017 - frontiersin.org
Exosomes are endosomal origin membrane-enclosed small vesicles (30–100 nm) that
contain various molecular constituents including proteins, lipids, mRNAs and microRNAs …
contain various molecular constituents including proteins, lipids, mRNAs and microRNAs …
Intravenous autologous bone marrow mononuclear cells for ischemic stroke
SI Savitz, V Misra, M Kasam, H Juneja… - Annals of …, 2011 - Wiley Online Library
Objective: Cellular therapy is an investigational approach for stroke. Mononuclear cells
(MNCs) from the bone marrow reduce neurological deficits in animal stroke models. We …
(MNCs) from the bone marrow reduce neurological deficits in animal stroke models. We …
Umbilical cord blood therapy potentiated with erythropoietin for children with cerebral palsy: a double-blind, randomized, placebo-controlled trial
Allogeneic umbilical cord blood (UCB) has therapeutic potential for cerebral palsy (CP).
Concomitant administration of recombinant human erythropoietin (rhEPO) may boost the …
Concomitant administration of recombinant human erythropoietin (rhEPO) may boost the …
Neural stem cell therapy—Brief review
C Grochowski, E Radzikowska… - Clinical neurology and …, 2018 - Elsevier
Adult mammalian neural stem cells are unique because of their properties, such as
differentiation capacity, self-renewal, quiescence, and also because they exist in specific …
differentiation capacity, self-renewal, quiescence, and also because they exist in specific …