Design principles governing the development of theranostic anticancer agents and their nanoformulations with photoacoustic properties

SG Kyrkou, EI Vrettos, D Gorpas, T Crook, N Syed… - Pharmaceutics, 2022 - mdpi.com
The unmet need to develop novel approaches for cancer diagnosis and treatment has led to
the evolution of theranostic agents, which usually include, in addition to the anticancer drug …

[HTML][HTML] Irinotecan-loaded magnetite-silica core-shell systems for colorectal cancer treatment

C Chircov, MC Petcu, BS Vasile, B Purcăreanu… - International Journal of …, 2024 - Elsevier
Colorectal cancer represents a worldwide spread type of cancer and it is regarded as one of
the leading death causes, along with lung, breast, and prostate cancers. Since conventional …

Ex vivo model of human skin (hOSEC) for assessing the dermatokinetics of the anti-melanoma drug Dacarbazine

MN Leite, JSR Viegas, FSG Praça, NA de Paula… - European Journal of …, 2021 - Elsevier
Alternative models to replace animals in experimental studies remain a challenge in testing
the effectiveness of dermatologic and cosmetic drugs. We proposed a model of human …

Validação do modelo ex vivo de pele humana (hOSEC) para ensaio de absorção de insumos farmacêuticos

MN Leite - 2021 - teses.usp.br
Métodos alternativos ao uso de animais vêm sendo estudados e desenvolvidos ao longo
dos anos, merecendo destaque a cultura de explante de pele organotípica humana …