Distal colonocytes targeted by C. rodentium recruit T-cell help for barrier defence

CL Zindl, CG Wilson, AS Chadha, LW Duck, B Cai… - Nature, 2024 - nature.com
Abstract Interleukin 22 (IL-22) has a non-redundant role in immune defence of the intestinal
barrier,–. T cells, but not innate lymphoid cells, have an indispensable role in sustaining the …

Enteropathogenic E. coli infection co-elicits lysosomal exocytosis and lytic host cell death

R Shtuhin-Rahav, A Olender, E Zlotkin-Rivkin… - Mbio, 2023 - Am Soc Microbiol
Enteropathogenic Escherichia coli (EPEC) is a primary human enteric bacterial pathogen
causing acute diarrhea in children. EPEC colonizes the small intestine, and the disease is …

EspH utilizes phosphoinositide and Rab binding domains to interact with plasma membrane infection sites and Rab GTPases

I Nandi, RP Ramachandran, DE Shalev… - Gut …, 2024 - Taylor & Francis
Enteropathogenic E. coli (EPEC) is a Gram-negative bacterial pathogen that causes
persistent diarrhea. Upon attachment to the apical plasma membrane of the intestinal …