[HTML][HTML] Understanding the role of autophagy in cancer formation and progression is a real opportunity to treat and cure human cancers

S Patergnani, S Missiroli, G Morciano, M Perrone… - Cancers, 2021 - mdpi.com
Simple Summary The modulation of autophagy represents a potential therapeutic strategy
for cancer. More than one hundred clinical trials have been conducted or are ongoing to …

[HTML][HTML] The regulatory role of autophagy-related miRNAs in lung cancer drug resistance

M Shahverdi, K Hajiasgharzadeh, AD Sorkhabi… - Biomedicine & …, 2022 - Elsevier
Autophagy is conserved cellular machinery that degrades un-usable proteins and cellular
components and has a crucial role in the pathogenesis and drug resistance of various …

A novel autophagy‐related lncRNA survival model for lung adenocarcinoma

L Wu, Z Wen, Y Song, L Wang - Journal of cellular and …, 2021 - Wiley Online Library
Long non‐coding RNA (lncRNA) is an important regulatory factor in the development of lung
adenocarcinoma, which is related to the control of autophagy. LncRNA can also be used as …

[HTML][HTML] A prognostic model for overall survival of patients with early-stage non-small cell lung cancer: a multicentre, retrospective study.

C Lu, K Bera, X Wang, P Prasanna, J Xu… - The Lancet. Digital …, 2020 - thelancet.com
Background Intratumoural heterogeneity has been previously shown to be related to clonal
evolution and genetic instability and associated with tumour progression. Phenotypically, it …

[HTML][HTML] Identification of a novel tumor microenvironment–associated eight-gene signature for prognosis prediction in lung adenocarcinoma

C Ma, H Luo, J Cao, X Zheng, J Zhang… - Frontiers in molecular …, 2020 - frontiersin.org
Background Lung cancer has become the most common cancer type and caused the most
cancer deaths. Lung adenocarcinoma (LUAD) is one of the major types of lung cancer …

CCL2 promotes metastasis and epithelial–mesenchymal transition of non‐small cell lung cancer via PI3K/Akt/mTOR and autophagy pathways

H Xu, J Wang, M Al‐Nusaif, H Ma, W Le - Cell Proliferation, 2024 - Wiley Online Library
In non‐small cell lung cancer (NSCLC), metastasis is the most common phenotype, and
autophagy plays a vital role in its regulation. However, there are limited data on how …

[HTML][HTML] The comprehensive analysis identified an autophagy signature for the prognosis and the immunotherapy efficiency prediction in lung adenocarcinoma

X Li, Z Dai, X Wu, N Zhang, H Zhang, Z Wang… - Frontiers in …, 2022 - frontiersin.org
Background Lung adenocarcinoma (LUAD) is a fatal malignancy in the world. Growing
evidence demonstrated that autophagy-related genes regulated the immune cell infiltration …

[HTML][HTML] Prognostic implication of a metabolism-associated gene signature in lung adenocarcinoma

L He, J Chen, F Xu, J Li - Molecular Therapy-Oncolytics, 2020 - cell.com
Lung cancer is the most common cancer worldwide, leading to high mortality each year.
Metabolic pathways play a vital role in the initiation and progression of lung cancer. We …

[HTML][HTML] Prognostic value of fatty acid metabolism-related genes in patients with hepatocellular carcinoma

D He, L Cai, W Huang, Q Weng, X Lin, M You… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
The deregulation of fatty acid metabolism plays a crucial role in cancer. However, the
prognostic value of genes involved in the metabolism in hepatocellular carcinoma (HCC) …

[HTML][HTML] Identification and validation of an individualized autophagy-clinical prognostic index in gastric cancer patients

J Qiu, M Sun, Y Wang, B Chen - Cancer cell international, 2020 - Springer
Background The purpose of this study is to perform bioinformatics analysis of autophagy-
related genes in gastric cancer, and to construct a multi-gene joint signature for predicting …