Pharmacologically active phytomolecules isolated from traditional antidiabetic plants and their therapeutic role for the management of diabetes mellitus

P Ansari, S Akther, JMA Hannan, V Seidel, NJ Nujat… - Molecules, 2022 - mdpi.com
Diabetes mellitus is a chronic complication that affects people of all ages. The increased
prevalence of diabetes worldwide has led to the development of several synthetic drugs to …

Alkaloidal phytoconstituents for diabetes management: exploring the unrevealed potential

T Behl, A Gupta, M Albratty, A Najmi, AM Meraya… - Molecules, 2022 - mdpi.com
The main characteristic feature of diabetes mellitus is the disturbance of carbohydrate, lipid,
and protein metabolism, which results in insulin insufficiency and can also lead to insulin …

Papaverine: a miraculous alkaloid from opium and its multimedicinal application

S Ashrafi, S Alam, A Sultana, A Raj, NU Emon, FT Richi… - Molecules, 2023 - mdpi.com
The pharmacological actions of benzylisoquinoline alkaloids are quite substantial, and have
recently attracted much attention. One of the principle benzylisoquinoline alkaloids has been …

Type 1 Diabetes Mellitus: A Review on Advances and Challenges in Creating Insulin Producing Devices

SM Rodrigues Oliveira, A Rebocho, E Ahmadpour… - Micromachines, 2023 - mdpi.com
Type 1 diabetes mellitus (T1DM) is the most common autoimmune chronic disease in young
patients. It is caused by the destruction of pancreatic endocrine β-cells that produce insulin …

A review on phytochemical and pharmacological facets of tropical ethnomedicinal plants as reformed DPP-IV inhibitors to regulate incretin activity

S Chhabria, S Mathur, S Vadakan, DK Sahoo… - Frontiers in …, 2022 - frontiersin.org
Type 2 diabetes mellitus is a metabolic disorder resulting from impaired insulin secretion
and resistance. Dipeptidyl peptidase (DPP)-IV is an enzyme known to trigger the catalysis of …

iPADD: a computational tool for predicting potential antidiabetic drugs using machine learning algorithms

XW Liu, TY Shi, D Gao, CY Ma, H Lin… - Journal of Chemical …, 2023 - ACS Publications
Diabetes mellitus is a chronic metabolic disease, which causes an imbalance in blood
glucose homeostasis and further leads to severe complications. With the increasing …

Antioxidant and Anti-Diabetic Properties of Olive (Olea europaea) Leaf Extracts: In Vitro and In Vivo Evaluation

HMM Mansour, AA Zeitoun, HS Abd-Rabou… - Antioxidants, 2023 - mdpi.com
(1) Objective: The main objective of the current study was to evaluate in vitro and in vivo an
antioxidant property of three genotypes of olive leaf extract (OLE)(picual, tofahi and …

Protective effects of medicinal plant-based foods against diabetes: a review on pharmacology, phytochemistry, and molecular mechanisms

P Ansari, JF Samia, JT Khan, MR Rafi, MS Rahman… - Nutrients, 2023 - mdpi.com
Diabetes mellitus (DM) comprises a range of metabolic disorders characterized by high
blood glucose levels caused by defects in insulin release, insulin action, or both. DM is a …

Green synthesis of silver nanoparticles: optimizing green tea leaf extraction for enhanced physicochemical properties

A Wirwis, Z Sadowski - ACS omega, 2023 - ACS Publications
In this paper, we present the optimization of green tea leaf (Camellia sinensis L.) extraction,
carried out using water and hydroalcoholic solvents, for the subsequent synthesis of silver …

Angiogenic and osteogenic effects of flavonoids in bone regeneration

A Shanmugavadivu… - Biotechnology and …, 2022 - Wiley Online Library
Bone is a highly vascularized tissue that relies on a close spatial and temporal interaction
between blood vessels and bone cells. As a result, angiogenesis is critical for bone …