Long-axial field-of-view PET/CT: perspectives and review of a revolutionary development in nuclear medicine based on clinical experience in over 7000 patients

I Alberts, H Sari, C Mingels, A Afshar-Oromieh, T Pyka… - Cancer Imaging, 2023 - Springer
Recently introduced long-axial field-of-view (LAFOV) PET/CT systems represent one of the
most significant advancements in nuclear medicine since the advent of multi-modality …

HIV persistence in subsets of CD4+ T cells: 50 shades of reservoirs

R Fromentin, N Chomont - Seminars in immunology, 2021 - Elsevier
Antiretroviral therapy controls HIV replication but does not eliminate the virus from the
infected host. The persistence of a small pool of cells harboring integrated and replication …

New PET technologies–embracing progress and pushing the limits

N Aide, C Lasnon, A Kesner, CS Levin, I Buvat… - European journal of …, 2021 - Springer
Thanks to companies' research and development processes, frequently involving fruitful
partnerships with academic centres, and what could be acknowledged as welcome …

Total-body PET/CT–first clinical experiences and future perspectives

QKT Ng, EKA Triumbari, N Omidvari, SR Cherry… - Seminars in nuclear …, 2022 - Elsevier
Total-body PET has come a long way from its first conception to today, with both total-body
and long axial field of view (> 1m) scanners now being commercially available world-wide …

Total-body PET kinetic modeling and potential opportunities using deep learning

Y Wang, E Li, SR Cherry, G Wang - PET clinics, 2021 - pet.theclinics.com
PET is a sensitive molecular imaging method that uses radiolabeled tracers to monitor the
biological and physiologic function of the scanned subject in vivo. 1 PET is commonly used …

Quantitative accuracy in total-body imaging using the uEXPLORER PET/CT scanner

EK Leung, E Berg, N Omidvari… - Physics in medicine …, 2021 - iopscience.iop.org
Absolute quantification of regional tissue concentration of radioactivity in positron emission
tomography (PET) is a critical parameter-of-interest across various clinical and research …

3D melanoma spheroid model for the development of positronium biomarkers

H Karimi, P Moskal, A Żak, EŁ Stępień - Scientific Reports, 2023 - nature.com
It was recently demonstrated that newly invented positronium imaging may be used for
improving cancer diagnostics by providing additional information about tissue pathology …

Artificial intelligence-based joint attenuation and scatter correction strategies for multi-tracer total-body PET

H Sun, Y Huang, D Hu, X Hong, Y Salimi, W Lv… - EJNMMI physics, 2024 - Springer
Background Low-dose ungated CT is commonly used for total-body PET attenuation and
scatter correction (ASC). However, CT-based ASC (CT-ASC) is limited by radiation dose …

HIV compartmentalization in the CNS and its impact in treatment outcomes and cure strategies

P Chan, S Spudich - Current HIV/AIDS Reports, 2022 - Springer
Abstract Purpose of Review This review focuses on the cerebrospinal fluid (CSF) findings in
connection to the central nervous system (CNS) reservoir in treatment-naïve and virally …

Practical Considerations for Total-Body PET Acquisition and Imaging

BA Spencer, K McBride, H Hunt, T Jones… - … : Methods and Protocols, 2023 - Springer
The world's first total-body PET/CT system has been in routine clinical and research use at
UC Davis since 2019. The uEXPLORER total-body PET scanner has been designed with an …