The application of biocompatible nanocarriers in medicine has provided several benefits
over conventional treatment methods. However, achieving high treatment efficacy and deep …

Therapeutic ultrasound strategies that harness the mechanical activity of cavitation nuclei for
beneficial tissue bio-effects are actively under development. The mechanical oscillations of …

Magnetic resonance-guided focused ultrasound in combination with intravenously injected
microbubbles has been shown to transiently open the blood–brain barrier, and reduce beta …

The blood-brain barrier (BBB) has long limited therapeutic access to brain tumor and
peritumoral tissue. In animals, MR-guided focused ultrasound (MRgFUS) with intravenously …

Blood-brain barrier (BBB) remains a significant obstacle to drug therapy for brain diseases.
Focused ultrasound (FUS) combined with microbubbles (MBs) can locally and transiently …

Ultrasound-responsive polymeric materials have received a tremendous amount of attention
from scientists for several decades. Compared to other stimuli-responsive materials (such as …

Pharmacological treatment of gliomas and other brain-infiltrating tumors remains
challenging due to limited delivery of most therapeutics across the blood–brain barrier …

Cavitation-facilitated microbubble-mediated focused ultrasound therapy is a promising
method of drug delivery across the blood–brain barrier (BBB) for treating many neurological …

In the last couple of decades, ultrasound-driven microbubbles have proven excellent
candidates for local drug delivery applications. Besides being useful drug carriers …

The physiology of the vasculature in the central nervous system (CNS), which includes the
blood–brain barrier (BBB) and other factors, complicates the delivery of most drugs to the …