The type VII protein secretion system (T7SS) of Staphylococcus aureus is encoded at the
ess locus. T7 substrate recognition and protein transport are mediated by EssC, a …

Gram‐negative bacteria have evolved numerous pathways to secrete proteins across their
complex cell envelopes. Here, we describe a protein secretion system that uses a holin …

Bacteria have evolved diverse immunity mechanisms to protect themselves against the
constant onslaught of bacteriophages,–. Similar to how eukaryotic innate immune systems …

Toxin-antitoxin (TA) systems are a large group of small genetic modules found in
prokaryotes and their mobile genetic elements. Type II TAs are encoded as bicistronic (two …

CRISPR defence systems such as the well-known DNA-targeting Cas9 and the RNA-
targeting type III systems are widespread in prokaryotes,. The latter orchestrates a complex …

Prokaryotes have evolved a multitude of defense systems to protect against phage
predation. Some of these resemble eukaryotic genes involved in antiviral responses. Here …

The type VII protein secretion system (T7SS) is found in many Gram-positive bacteria and in
pathogenic mycobacteria. All T7SS substrate proteins described to date share a common …

This review covers literature between 2003–2021 The development and application of
genome mining tools has given rise to ever-growing genetic and chemical databases and …

RNA-binding proteins (RPBs) are deeply involved in fundamental cellular processes in
bacteria and are vital for their survival. Despite this, few studies have so far been dedicated …

Abstract Model organisms such as the Gram‐positive bacterium Bacillus subtilis have been
studied intensively for decades. However, even for model organisms, no function has been …