Primary sclerosing cholangitis, a chronic cholestatic liver disease of unknown cause, is
characterized by ongoing inflammation, destruction, and fibrosis of intrahepatic and …

Extraintestinal manifestations in patients withinflammatory bowel disease (IBD) are quite
common (about25%) and careful clinical observation and statisticalanalysis during the last …

BACKGROUND/AIMS--The course of primary sclerosing cholangitis (PSC) is highly variable
and unpredictable. This study describes the natural history and outcome of PSC. These data …

OBJECTIVES Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with
varying severity and progression. This study describes the natural history of PSC patients …

Metabolic processes utilize a variety of differing and contrasting biochemical routes to
enable synthesis of degradation and activation or deactivation of substances; in addition …

We established six T cell clones specific for pyruvate dehydrogenase complex (PDC)-E2
peptides from four different patients with primary biliary cirrhosis using 33 different peptides …

Primary biliary cirrhosis (PBC) is an organ‐specific autoimmune disease that predominantly
affects women and is characterized by chronic progressive destruction of small intrahepatic …

Background & Aims: Remission of several autoimmune diseases has been described after
allogeneic marrow transplantation. The aim of this study was to determine if the natural …

The clinical presentation and outcome of 32 children with primary sclerosing cholangitis
(PSC) are reviewed, the largest North American series. The majority of patients were …

The incidence of primary sclerosing cholangitis has been estimated on the basis of its
frequent association with ulcerative colitis, but direct epidemiologic studies have not yet …