Myofibroblasts: function, formation, and scope of molecular therapies for skin fibrosis

Y Tai, EL Woods, J Dally, D Kong, R Steadman… - Biomolecules, 2021 - mdpi.com
Myofibroblasts are contractile, α-smooth muscle actin-positive cells with multiple roles in
pathophysiological processes. Myofibroblasts mediate wound contractions, but their …

A concise review on tissue engineered artificial skin grafts for chronic wound treatment: can we reconstruct functional skin tissue in vitro?

A Przekora - Cells, 2020 - mdpi.com
Chronic wounds occur as a consequence of a prolonged inflammatory phase during the
healing process, which precludes skin regeneration. Typical treatment for chronic wounds …

Hypoxia adipose stem cell-derived exosomes promote high-quality healing of diabetic wound involves activation of PI3K/Akt pathways

J Wang, H Wu, Y Peng, Y Zhao, Y Qin, Y Zhang… - Journal of …, 2021 - Springer
Refractory diabetic wounds can cause persistent inflammation and delayed healing due to
hypoxia. Currently, no optimal solution is available. Exosomes of adipose stem cells (ADSCs …

Exosomes derived from human adipose mensenchymal stem cells accelerates cutaneous wound healing via optimizing the characteristics of fibroblasts

LI Hu, J Wang, X Zhou, Z Xiong, J Zhao, R Yu… - Scientific reports, 2016 - nature.com
Prolonged healing and scar formation are two major challenges in the treatment of soft
tissue trauma. Adipose mesenchymal stem cells (ASCs) play an important role in tissue …

Exosomes derived from epidermal stem cells improve diabetic wound healing

P Wang, G Theocharidis, IS Vlachos, K Kounas… - Journal of Investigative …, 2022 - Elsevier
Diabetic foot ulceration is a major diabetic complication with unmet needs. We investigated
the efficacy of epidermal stem cells and epidermal stem cells–derived exosomes (ESCs …

Prospective application of exosomes derived from adipose‐derived stem cells in skin wound healing: A review

H Qiu, S Liu, K Wu, R Zhao, L Cao… - Journal of cosmetic …, 2020 - Wiley Online Library
Background Wound healing has always been an intractable medical problem for both
clinicians and researchers and a burden for patients both physically and financially. Poor …

Combined topical and systemic administration with human adipose-derived mesenchymal stem cells (hADSC) and hADSC-derived exosomes markedly promoted …

Y Zhou, B Zhao, XL Zhang, Y Lu, ST Lu… - Stem cell research & …, 2021 - Springer
Background Cutaneous wound healing and regeneration have become a recognized health
challenge in the world, which causes severe damage to the mental and physical health of …

Healing of chronic wounds: an update of recent developments and future possibilities

MH Kathawala, WL Ng, D Liu, MW Naing… - … Engineering Part B …, 2019 - liebertpub.com
Chronic wounds are the result of disruptions in the body's usual process of healing. They are
not only a source of significant pain and discomfort but also, more importantly, an unguarded …

A Comparative Study of the ReCell® Device and Autologous Split-Thickness Meshed Skin Graft in the Treatment of Acute Burn Injuries

JH Holmes Iv, JA Molnar, JE Carter… - Journal of Burn Care …, 2018 - academic.oup.com
Early excision and autografting are standard care for deeper burns. However, donor sites
are a source of significant morbidity. To address this, the ReCell® Autologous Cell …

The current role of three-dimensional printing in plastic surgery

P Kamali, D Dean, R Skoracki… - Plastic and …, 2016 - journals.lww.com
Since the advent of three-dimensional printing in the 1980s, it has become possible to
produce physical objects from digital files and create three-dimensional objects by adding …