CRISPR/Cas9 gene editing: a new approach for overcoming drug resistance in cancer
M Vaghari-Tabari, P Hassanpour… - Cellular & Molecular …, 2022 - Springer
The CRISPR/Cas9 system is an RNA-based adaptive immune system in bacteria and
archaea. Various studies have shown that it is possible to target a wide range of human …
archaea. Various studies have shown that it is possible to target a wide range of human …
The pentose phosphate pathway in cancer: regulation and therapeutic opportunities
N Ghanem, C El-Baba, K Araji, R El-Khoury, J Usta… - Chemotherapy, 2021 - karger.com
Background: Tumorigenesis is associated with deregulation of nutritional requirements,
intermediary metabolites production, and microenvironment interactions. Unlike their normal …
intermediary metabolites production, and microenvironment interactions. Unlike their normal …
[HTML][HTML] A network pharmacology approach and experimental validation to investigate the anticancer mechanism of Qi-Qin-Hu-Chang formula against colitis …
Y Wu, Y Fang, Y Li, R Au, C Cheng, W Li, F Xu… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance The Qi-Qin-Hu-Chang Formula (QQHCF) is a
traditional Chinese medicine prescription that is clinically used at the Affiliated Hospital of …
traditional Chinese medicine prescription that is clinically used at the Affiliated Hospital of …
Ferulic acid: a review of pharmacology, toxicology, and therapeutic effects on pulmonary diseases
Y Zhai, T Wang, Y Fu, T Yu, Y Ding, H Nie - International Journal of …, 2023 - mdpi.com
Ferulic acid (FA), a prevalent dietary phytochemical, has many pharmacological effects,
including anti-oxidation and anti-inflammation effects, and has been widely used in the …
including anti-oxidation and anti-inflammation effects, and has been widely used in the …
Metabolic control of cancer metastasis: role of amino acids at secondary organ sites
B Karno, DN Edwards, J Chen - Oncogene, 2023 - nature.com
Most cancer-related deaths are caused by the metastases, which commonly develop at
multiple organ sites including the brain, bone, and lungs. Despite longstanding observations …
multiple organ sites including the brain, bone, and lungs. Despite longstanding observations …
Novel roles of PIWI proteins and PIWI-interacting RNAs in human health and diseases
Z Wu, X Yu, S Zhang, Y He, W Guo - Cell Communication and Signaling, 2023 - Springer
Non-coding RNA has aroused great research interest recently, they play a wide range of
biological functions, such as regulating cell cycle, cell proliferation, and intracellular …
biological functions, such as regulating cell cycle, cell proliferation, and intracellular …
Sirtuin1-p53: a potential axis for cancer therapy
J Yin, X Lu, M Hou, T Cao, Z Tian - Biochemical pharmacology, 2023 - Elsevier
Abstract Sirtuin1 (SIRT1) is a conserved nicotinamide adenine dinucleotide (NAD+)-
dependent histone deacetylase that plays key roles in a range of cellular events, including …
dependent histone deacetylase that plays key roles in a range of cellular events, including …
Association between triglyceride glucose index and risk of cancer: A meta-analysis
H Wang, F Yan, Y Cui, F Chen, G Wang… - Frontiers in …, 2023 - frontiersin.org
Background Triglyceride glucose (TyG) index as a more convenient and reliable predictor of
insulin resistance (IR) is thought to be associated with many diseases, but its relationship …
insulin resistance (IR) is thought to be associated with many diseases, but its relationship …
Mitochondrion-targeted selenium nanoparticles stabilized by Sargassum fusiforme polysaccharides increase reactive oxygen species-mediated antitumour activity
Y Chen, F Zhu, J Ou, J Chen, X Liu, R Li, Z Wang… - International Journal of …, 2024 - Elsevier
Authors prepared a nanoselenium particle stabilized with Sargassum fusiforme
polysaccharide (SFPS-Tw-SeNPs) and confirmed that it could effectively inhibit the …
polysaccharide (SFPS-Tw-SeNPs) and confirmed that it could effectively inhibit the …
Tyrosine phosphatase PTPN11/SHP2 in solid tumors - bull's eye for targeted therapy?
X Chen, SJ Keller, P Hafner, AY Alrawashdeh… - Frontiers in …, 2024 - frontiersin.org
Encoded by PTPN11, the Src-homology 2 domain-containing phosphatase 2 (SHP2)
integrates signals from various membrane-bound receptors such as receptor tyrosine …
integrates signals from various membrane-bound receptors such as receptor tyrosine …