A novel C-type lectin (CLEC12B) from Nile tilapia (Oreochromis niloticus) is involved in host defense against bacterial infection

Z Zhang, J Niu, Q Li, Y Huang, B Jiang, X Li… - Fish & Shellfish …, 2022 - Elsevier
C-type lectin (CLEC) is a family of carbohydrate-binding protein that has high affinity for
calcium and mediates multiple biological events including adhesion between cells, the …

Molecular characterization and functional analysis of CD209E from Nile Tilapia (Oreochromis Niloticus) involved in immune response to bacterial infection

Y Wu, M Huang, Y Lu, Y Huang, J Jian - Fish & Shellfish Immunology, 2023 - Elsevier
CD209 plays significant roles in pathogen recognition, innate and adaptive immunity, and
cell-cell interactions. In the present study, a CD209 antigen-like protein E from Nile tilapia …

A novel perlucin-like protein (PLP) protects Litopenaeus vannamei against Vibrio harveyi infection

J Feng, Y Huang, M Huang, J Luo, L Que… - Fish & Shellfish …, 2023 - Elsevier
Abstract C-type lectins (CTLs), as pattern recognition receptors (PRRs), play an important
role in the innate immunity of Litopenaeus vannamei. In this study, a novel CTL, named …

[HTML][HTML] Vasoactive Intestinal Peptide (VIP) Protects Nile Tilapia (Oreochromis niloticus) against Streptococcus agalatiae Infection

Z Zhang, Q Li, Y Huang, Z Xu, X Chen, B Jiang… - International Journal of …, 2022 - mdpi.com
Vasoactive intestinal peptide (VIP), a member of secretin/glucagon family, is involved in a
variety of biological activities such as gut motility, immune responses, and carcinogenesis. In …

[HTML][HTML] Selection and evaluation of stable reference genes for quantitative real-time PCR in the head kidney leukocyte of Oreochromis niloticus

B Jiang, Q Li, Z Zhang, Y Huang, Y Wu, X Li… - Aquaculture …, 2023 - Elsevier
To investigate the antibacterial mechanisms of Nile tilapia, it is necessary to understand the
responses of immune-related genes in infected lymphocytes. Usually, quantitative real-time …

[HTML][HTML] Japanese flounder HMGB1: A DAMP molecule that promotes antimicrobial immunity by interacting with immune cells and bacterial pathogen

Y Chen, C Yu, S Jiang, L Sun - Genes, 2022 - mdpi.com
High mobility group box (HMGB) proteins are DNA-associated proteins that bind and
modulate chromosome structures. In mammals, HMGB proteins can be released from the …

[HTML][HTML] Molecular characterization of a novel C-type lectin receptors (CD302) in Nile tilapia (Oreochromis niloticus) and its functional analysis in host defense against …

Z Zhang, Q Li, Y Huang, B Jiang, X Li, M Huang… - Aquaculture …, 2022 - Elsevier
C-type lectin receptors (CLRs) are a group of carbohydrate-binding proteins which function
by mediating multiple biological events, including adhesion between cells, the turnover of …

Siglec7 functions as an inhibitory receptor of non-specific cytotoxic cells and can regulate the innate immune responses in a primitive vertebrate (Oreochromis …

Z Zhang, X Li, M Huang, Y Huang, X Tan… - International Journal of …, 2024 - Elsevier
In mammals, siglec7, an integral component of the siglecs, is principally found on the
surface of natural killer (NK) cells, macrophages, and monocytes, where it interacts with …

The role of HMGB2 in the immune response of Nile tilapia (Oreochromis niloticus) to streptococcal infection

Y Dong, Z Zhang, Y Huang, X Tan, X Li… - Fish & Shellfish …, 2024 - Elsevier
High mobility group protein B2 (HMGB2) is an abundant chromatin-associated protein with
pivotal roles in transcription, cell proliferation, differentiation, inflammation, and …

[HTML][HTML] Transferrin Mediated NCC Killing Activity through NCCRP-1 in Nile Tilapia (Oreochromis niloticus)

Y Huang, Z Chen, R Xie, P Wang, Z Zhang, J Cai… - Fishes, 2022 - mdpi.com
Non-specific cytotoxic cell l (NCC) is a kind of important lymphocyte participating in the non-
specific immune response in teleost. Non-specific cytotoxic cell receptor protein 1 (NCCRP …