The present review aims to provide an update on health risks associated with the low-to-
moderate levels of environmental cadmium (Cd) and lead (Pb) to which most populations …

Environmental and occupational exposure to heavy metals and metalloids is a major global
health risk. The kidney is often a site of early damage. Nephrotoxicity is both a major …

Background The absorption and accumulation of cadmium (Cd) within the human body can
be influenced by the status of certain micronutrients, while available evidence for the …

The objective of the present study was to examine the effects of long-term exposure on
oxidative damage, Keap1/Nrf2 signaling pathway, and Msr-related redox status in the …

Background In kidney damage, molecular changes can be used as early damage kidney
biomarkers, such as Kidney Injury Molecule-1 and Neutrophil gelatinase-associated …

The accumulation of copper (Cu) in the organisms could lead to kidney damage by causing
mitochondrial dysfunction. Given that mitochondria are one of the targets of Cu poisoning …

Abstract N 6-methyladenosine (m 6 A) modification and m 6 A-modified Long non-coding
RNAs (LncRNAs) play crucial roles in various pathological processes, yet their changes and …

The nephrotoxicity of low-chronic metal exposures is unclear, especially considering several
metals simultaneously. We assessed the individual and joint association of metals with …

Fetal overexposure to active glucocorticoid (GC) is the major cause for fetal growth
restriction (FGR). This study investigated the influences of cadmium (Cd) exposure on active …

Vitamin C (ascorbic acid; AA) and copper (Cu2+) are well used supplements with many
health-promoting actions. However, when they are used in combination, the Fenton reaction …