Excess body weight has been established as a risk factor for at least twelve cancer sites,
though questions remain as to the timing of associations for adiposity and cancer risk …

Research methods to study risk factors and prevention of breast cancer have evolved
rapidly. We focus on advances from epidemiologic studies reported over the past two …

The unexplained protective effect of childhood adiposity on breast cancer risk may be
mediated via mammographic density (MD). Here, we investigate a complex relationship …

Aims Previous Mendelian randomization (MR) of obesity and diabetic nephropathy (DN) risk
used small sample sizes or focused on a single adiposity metric. We explored the …

Breast cancer has become the most common malignancy among women, posing a severe
health risk to women worldwide and creating a heavy social burden. Based on current …

Objective In numerous observational studies, there has been an indication that educational
attainment (EA) can impact the intensity of pain and disability resulting from chronic …

Hao et al. 1 present an extensive examination of the role of adiposity in female breast cancer
(BC) using comprehensive Mendelian randomization (MR) methods. Previous MR studies of …

Multivariable Mendelian randomization (MVMR) uses genetic variants as instrumental
variables to infer the direct effect of multiple exposures on an outcome. Compared to …

Observational studies suggest that mammographic density (MD) may have a role in the
unexplained protective effect of childhood adiposity on breast cancer risk. Here, we …

目的采用孟德尔随机化(MR) 方法探讨饮茶与恶性肿瘤发病之间的关联. 方法利用中国慢性病
前瞻性研究中100 639 名具有全基因组基因分型数据的研究对象, 剔除基线时患有恶性肿瘤的 …