The biological and clinical significance of emerging SARS-CoV-2 variants
The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …
spike protein mutations that are influencing the epidemiological and clinical aspects of the …
Omicron: what makes the latest SARS-CoV-2 variant of concern so concerning?
Emerging strains of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the
causative agent of the coronavirus disease 2019 (COVID-19) pandemic, that show …
causative agent of the coronavirus disease 2019 (COVID-19) pandemic, that show …
Ecology, evolution and spillover of coronaviruses from bats
In the past two decades, three coronaviruses with ancestral origins in bats have emerged
and caused widespread outbreaks in humans, including severe acute respiratory syndrome …
and caused widespread outbreaks in humans, including severe acute respiratory syndrome …
[HTML][HTML] Mutations in SARS-CoV-2: Insights on structure, variants, vaccines, and biomedical interventions
COVID-19 is a worldwide pandemic caused by SARS-coronavirus-2 (SARS-CoV-2). Less
than a year after the emergence of the Covid-19 pandemic, many vaccines have arrived on …
than a year after the emergence of the Covid-19 pandemic, many vaccines have arrived on …
Emerging SARS-CoV-2 mutation hot spots include a novel RNA-dependent-RNA polymerase variant
M Pachetti, B Marini, F Benedetti, F Giudici… - Journal of translational …, 2020 - Springer
Background SARS-CoV-2 is a RNA coronavirus responsible for the pandemic of the Severe
Acute Respiratory Syndrome (COVID-19). RNA viruses are characterized by a high mutation …
Acute Respiratory Syndrome (COVID-19). RNA viruses are characterized by a high mutation …
Remdesivir: a review of its discovery and development leading to emergency use authorization for treatment of COVID-19
The global pandemic of SARS-CoV-2, the causative viral pathogen of COVID-19, has driven
the biomedical community to action—to uncover and develop antiviral interventions. One …
the biomedical community to action—to uncover and develop antiviral interventions. One …
Emerging coronaviruses: genome structure, replication, and pathogenesis
Y Chen, Q Liu, D Guo - Journal of medical virology, 2020 - Wiley Online Library
The recent emergence of a novel coronavirus (2019‐nCoV), which is causing an outbreak of
unusual viral pneumonia in patients in Wuhan, a central city in China, is another warning of …
unusual viral pneumonia in patients in Wuhan, a central city in China, is another warning of …
Structural insights into SARS-CoV-2 proteins
The unprecedented scale of the ongoing COVID-19 pandemic has catalyzed an intense
effort of the global scientific community to unravel different aspects of the disease in a short …
effort of the global scientific community to unravel different aspects of the disease in a short …
Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex
SARS-CoV-2 is the causative agent of the 2019–2020 pandemic. The SARS-CoV-2 genome
is replicated and transcribed by the RNA-dependent RNA polymerase holoenzyme …
is replicated and transcribed by the RNA-dependent RNA polymerase holoenzyme …
A structural view of SARS-CoV-2 RNA replication machinery: RNA synthesis, proofreading and final capping
The current coronavirus disease-2019 (COVID-19) pandemic is due to the novel coronavirus
SARS-CoV-2. The scientific community has mounted a strong response by accelerating …
SARS-CoV-2. The scientific community has mounted a strong response by accelerating …