Anthracyclines currently play a key role in the treatment of many cancers, but the limiting
factor of their use is the widespread phenomenon of drug resistance and untargeted toxicity …

The kidneys are a pair of important organs that excretes endogenous waste and exogenous
biological agents from the body. Numerous transporters are involved in the excretion …

Purpose Since the discovery of the well-known cis-platin, transition metal complexes are
highly recognized as cytostatic agents. However, toxic side effects of the metal ions present …

Colchicine, the main active alkaloid from Colchicum autumnale L., is a potent tubulin binder
and represents an interesting lead structure for the development of potential anticancer …

Background: Herein, molecular docking approaches and DFT ab initio simulations were
combined for the first time, to study the key interactions of cyclodextrins (CDs: α-CD, β-CD …

Background: Praziquantel, as the only drug for the treatment of schistosomiasis, is under
serious threat due to the emergence of resistant strains of Schistosoma species. There is an …

Cervical Cancer (CC), even though it can reach high cure rates when early diagnosis
occurs, is a severe public health problem, especially in less developed regions, such as …

Los hongos Basidiomicetos de la Podredumbre Blanca son los más activos degradadores
de lignina en la naturaleza en virtud de que excretan enzimas ligninolíticas, entre ellas …