LRRC4 is a novel relatively specific gene, which displays significant down-regulation in
primary brain tumor biopsies and has the potential to suppress brain tumor growth. In this …

The recommendations listed in this document are, whenever possible, evidence based. An
extensive review was conducted on literature published through November 2012, and other …

The recommendations listed in this document are, whenever possible, evidence based. An
extensive review was conducted on literature published through March 1, 2020. Searches …

Aim This executive summary of the valvular heart disease guideline provides
recommendations for clinicians to diagnose and manage valvular heart disease as well as …

Background The use of synthetic material for reconstructive vascular surgery was first
reported during the early 1950s. Infection involving vascular graft prostheses is an …

Potential Biases Most studies of IE are affected by selection, survival, and referral bias. They
make it difficult to study the natural history of IE in the general population, because treated …

Purpose Identifying modifiable factors for sepsis-associated encephalopathy may help
improve patient care and outcomes. Methods We conducted a retrospective analysis of a …

Sepsis often is characterized by an acute brain dysfunction, which is associated with
increased morbidity and mortality. Its pathophysiology is highly complex, resulting from both …

Patients with infective endocarditis (IE) form a heterogeneous group, ranging from those
who are successfully treated with no adverse events, to those with severe complications and …

Background A brain abscess is a focal infection of the brain that begins as a localized area
of cerebritis. In immunocompetent patients, bacteria are responsible for> 95% of brain …