The role of inflammation and genetics in periodontal disease

BG Loos, TE Van Dyke - Periodontology 2000, 2020 - Wiley Online Library
Periodontitis is a complex disease:(a) various causative factors play a role simultaneously
and interact with each other; and (b) the disease is episodic in nature, and bursts of disease …

Periodontitis: from microbial immune subversion to systemic inflammation

G Hajishengallis - Nature reviews immunology, 2015 - nature.com
Periodontitis is a dysbiotic inflammatory disease with an adverse impact on systemic health.
Recent studies have provided insights into the emergence and persistence of dysbiotic oral …

Porphyromonas gingivalis: An Overview of Periodontopathic Pathogen below the Gum Line

KY How, KP Song, KG Chan - Frontiers in microbiology, 2016 - frontiersin.org
Periodontal disease represents a group of oral inflammatory infections initiated by oral
pathogens which exist as a complex biofilms on the tooth surface and cause destruction to …

Oral health in the elderly patient and its impact on general well-being: a nonsystematic review

JA Gil-Montoya, AL Ferreira de Mello… - … interventions in aging, 2015 - Taylor & Francis
Data on the oral health of the elderly depict a worrying situation, with an elevated
prevalence of caries and moderate periodontal disease, frequent edentulism, and numerous …

Periodontitis and atherosclerotic cardiovascular disease: consensus report of the Joint EFP/AAPWorkshop on Periodontitis and Systemic Diseases

MS Tonetti, TE Van Dyke… - Journal of …, 2013 - Wiley Online Library
Background: This consensus report is concerned with the association between periodontitis
and atherosclerotic cardiovascular disease (ACVD). Periodontitis is a chronic multifactorial …

Periodontal pathogens as risk factors of cardiovascular diseases, diabetes, rheumatoid arthritis, cancer, and chronic obstructive pulmonary disease—Is there cause for …

D Bourgeois, C Inquimbert, L Ottolenghi, F Carrouel - Microorganisms, 2019 - mdpi.com
Cardiovascular diseases, chronic obstructive pulmonary diseases, diabetes, rheumatoid
arthritis, and cancer are the most common noncommunicable diseases (NCDs). These …

Periodontal systemic associations: review of the evidence

GJ Linden, A Lyons… - Journal of periodontology, 2013 - Wiley Online Library
Aim: To critically appraise recent research into associations between periodontal disease
and systemic diseases and conditions specifically respiratory disease, chronic kidney …

Treatment of periodontitis improves the atherosclerotic profile: a systematic review and meta‐analysis

WJ Teeuw, DE Slot, H Susanto… - Journal of clinical …, 2014 - Wiley Online Library
Aim Systematic review and meta‐analyses to study the robustness of observations that
treatment of periodontitis improves the atherosclerotic profile. Material and Methods …

Periodontitis and Alzheimer's disease: a possible comorbidity between oral chronic inflammatory condition and neuroinflammation

FB Teixeira, MT Saito, FC Matheus… - Frontiers in aging …, 2017 - frontiersin.org
Periodontitis is an oral chronic infection/inflammatory condition, identified as a source of
mediators of inflammation into the blood circulation, which may contribute to exacerbate …

Infection and inflammatory mechanisms

TE Van Dyke, AJ Van Winkelhoff - Journal of clinical …, 2013 - Wiley Online Library
This introductory article examines the potential mechanisms that may play a role in the
associations between periodontitis and the systemic conditions being considered in the …