Twenty-five years ago, the first mammalian Transient Receptor Potential Canonical (TRPC)
channel was cloned, opening the vast horizon of the TRPC field. Today, we know that there …

When host cells are exposed to foreign particles, dead cells, or cell hazards, a sophisticated
process called phagocytosis begins. During this process, macrophages, dendritic cells, and …

Depression has a growing impact on public health. Accumulating evidence supports an
association between depression and increased immune system activity. IL-10 is a key …

Sugar-induced metabolic imbalances are a major health problem since an excessive
consumption of saccharides has been linked to greater obesity rates at a global level …

The transient receptor potential channel (TRP channel) family is a kind of non-specific cation
channel widely distributed in various tissues and organs of the human body, including the …

Metabolic syndrome (MS) is a complex pathology characterized by visceral adiposity, insulin
resistance, arterial hypertension, and dyslipidaemia. It has become a global epidemic …

Background Members of the transient receptor potential canonical (TRPC) protein family are
widely distributed in the hippocampus of mammals and exert respective and cooperative …

Transient receptor potential channel canonical 5 (TRPC5) is a non-selective ion channel;
ion influx through TRPC5 causes activation of downstream signaling pathways. In addition …

Thioredoxins (Trxs) play an important role in defending against oxidative stress and keeping
disulfide bonding correct to maintain protein function. Edwardsiella piscicida, a severe fish …

To date, several members of the transient receptor potential (TRP) channels which provide a
wide array of roles have been found in the gastrointestinal tract (GI). The goal of earlier …