[HTML][HTML] Temporal profiles describing markers of inflammation and metabolism during the transition period of pasture-based, seasonal-calving dairy cows

OK Spaans, B Kuhn-Sherlock, A Hickey… - Journal of Dairy …, 2022 - Elsevier
The physiology of the dairy cow while transitioning from pregnancy to lactation is complex,
with multifactorial processes studied extensively for the role they play in manifestation of …

[HTML][HTML] Relationships between metabolic profiles and gene expression in liver and leukocytes of dairy cows in early lactation

DC Wathes, Z Cheng, M Salavati, L Buggiotti… - Journal of dairy …, 2021 - Elsevier
Homeorhetic mechanisms assist dairy cows in the transition from pregnancy to lactation.
Less successful cows develop severe negative energy balance (NEB), placing them at risk …

Associations between circulating IGF-1 concentrations, disease status and the leukocyte transcriptome in early lactation dairy cows

DC Wathes, F Becker, L Buggiotti, MA Crowe, C Ferris… - Ruminants, 2021 - mdpi.com
Peripartum dairy cows commonly experience negative energy balance (EB) and
immunosuppression together with high incidences of infectious and metabolic disease. This …

Formation of blood neutrophil extracellular traps increases the mastitis risk of dairy cows during the transition period

LY Jiang, HZ Sun, RW Guan, F Shi, FQ Zhao… - Frontiers in …, 2022 - frontiersin.org
The current study was conducted to analyze the functions of blood neutrophils in transition
cows and their association with postpartum mastitis risk as indicated by somatic cell counts …

Comparison of the transcriptome in circulating leukocytes in early lactation between primiparous and multiparous cows provides evidence for age-related changes

L Buggiotti, Z Cheng, M Salavati, CD Wathes - BMC genomics, 2021 - Springer
Background Previous studies have identified many immune pathways which are consistently
altered in humans and model organisms as they age. Dairy cows are often culled at quite …

Non-coding transcriptomic profiles in the sheep mammary gland during different lactation periods

W Chen, X Gu, X Lv, X Cao, Z Yuan… - Frontiers in veterinary …, 2022 - frontiersin.org
Sheep milk production is a dynamic and multifactorial trait regulated by diverse biological
mechanisms. To improve the quality and production of sheep milk, it is necessary to …

Proportion of concentrate in the diet of early lactation dairy cows has contrasting effects on circulating leukocyte global transcriptomic profiles, health and fertility …

Z Cheng, DL McLaughlin, MW Little, C Ferris… - International Journal of …, 2022 - mdpi.com
The functionality of circulating leukocytes in dairy cows is suppressed after calving, with
negative energy balance as a risk factor. Leukocyte transcriptomic profiles were compared …

[HTML][HTML] Inflammation, migration, and cell-cell interaction-related gene network expression in leukocytes is enhanced in Simmental compared with Holstein dairy cows …

V Lopreiato, A Minuti, VM Morittu, D Britti… - Journal of dairy …, 2020 - Elsevier
The aim of this study was to investigate changes in the abundance of genes involved in
leukocyte function between cows highly specialized for milk production (Holstein, n= 12) and …

Hydroxycarboxylic acid receptor 2 (HCA2) agonists induce NET formation and MMP-9 release from bovine polymorphonuclear leukocytes

MD Carretta, P Creutzburg, K Borquez… - Developmental & …, 2023 - Elsevier
Periparturient cows are commonly fed diets supplemented with Niacin (nicotinic acid, NA)
because of its anti-lipolytic properties. NA confers its anti-lipolytic effects by activating the …

[HTML][HTML] β-Hydroxybutyrate inhibits apoptosis in bovine neutrophils through activating ERK1/2 and AKT signaling pathways

Y Song, K Wang, JJ Loor, Q Jiang, Y Yang… - Journal of Dairy …, 2022 - Elsevier
Ketosis in dairy cows, a common metabolic disorder during the peripartal period, is
accompanied by systemic inflammation and high concentrations of blood β-hydroxybutyrate …