A proper dialogue between spermatozoa and the egg is essential for conception of a new
individual in sexually reproducing animals. Ca2+ is crucial in orchestrating this unique event …

Abstract Calcium ions (Ca 2+) are involved in nearly every aspect of cellular life. They are
one of the most abundant elements in mammals and play a vital role in physiological and …

Steroid hormone progesterone released by cumulus cells surrounding the egg is a potent
stimulator of human spermatozoa. It attracts spermatozoa towards the egg and helps them …

In the oviduct, cumulus cells that surround the oocyte release progesterone. In human
sperm, progesterone stimulates a Ca2+ increase by a non-genomic mechanism,,. The Ca2+ …

The infertility of many couples rests on an enigmatic dysfunction of the man's sperm. To gain
insight into the underlying pathomechanisms, we assessed the function of the sperm …

Abstract STUDY QUESTION Does CatSper have a role in the achievement of human sperm
motility and in the Progesterone (P)-induced acrosome reaction (AR)? SUMMARY ANSWER …

A disintegrin and metalloproteinase 3 (ADAM3) is a sperm membrane protein critical for both
sperm migration from the uterus into the oviduct and sperm primary binding to the zona …

Progesterone is a sexual steroid hormone that has a critical role in reproductive processes
in males and females of several species, including humans. Furthermore, progesterone has …

Navigation of sperm in fluid flow, called rheotaxis, provides long‐range guidance in the
mammalian oviduct. The rotation of sperm around their longitudinal axis (rolling) promotes …

Vitamin D is a versatile hormone with several functions beyond its well-established role in
maintenance of skeletal health and calcium homeostasis. The effects of vitamin D are …