Complement–HIV interactions during all steps of viral pathogenesis

H Stoiber, Z Banki, D Wilflingseder, MP Dierich - Vaccine, 2008 - Elsevier
Upon crossing the endothelial barrier of the host, HIV initiates immediate responses of the
immunity system. Among its components, the complement system is one of the first the first …

Complement-opsonized HIV: the free rider on its way to infection

H Stoiber, M Pruenster, CG Ammann, MP Dierich - Molecular immunology, 2005 - Elsevier
The complement system (C) is one of the main humoral components of innate immunity.
Three major tasks of C against invading pathogens are:(i) lysis of pathogens by the …

Characterization of binding properties of individual functional sites of human complement factor H

A Haque, C Cortes, MN Alam, M Sreedhar… - Frontiers in …, 2020 - frontiersin.org
Factor H exists as a 155,000 dalton, extended protein composed of twenty small domains
which is flexible enough that it folds back on itself. Factor H regulates complement activation …

Role of complement in the control of HIV dynamics and pathogenesis

H Stoiber, C Speth, MP Dierich - Vaccine, 2003 - Elsevier
In all ex vivo preparations of HIV tested so far, C3 fragments and, after seroconversion,
antibodies were detected on the viral surface. This indicates that HIV survives complement …

The role of properdin and Factor H in disease

C Cortes, C Desler, A Mazzoli, JY Chen… - Advances in …, 2022 - Elsevier
The complement system consists of three pathways (alternative, classical, and lectin) that
play a fundamental role in immunity and homeostasis. The multifunctional role of the …

Complement and antibodies: a dangerous liaison in HIV infection?

H Stoiber, A Soederholm, D Wilflingseder… - Vaccine, 2008 - Elsevier
Due to ongoing recombination and mutations, HIV permanently escapes from neutralizing
antibody (nAb) responses of the host. By the masking of epitopes or shedding of gp120, HIV …

Emerging role for complement in HIV infection

G Huber, Z Banki, S Lengauer… - Current Opinion in HIV …, 2011 - journals.lww.com
Emerging role for complement in HIV infection : Current Opinion in HIV and AIDS Emerging
role for complement in HIV infection : Current Opinion in HIV and AIDS Log in or Register …

Complement in different stages of HIV infection and pathogenesis

C Speth, H Stoiber, MP Dierich - International archives of allergy and …, 2003 - karger.com
The complement system is one of the most important weapons of innate immunity and is
involved in all infectious processes. It is not only a mechanism for direct protection against …

Complement, Fc receptors and antibodies: a Trojan horse in HIV infection?

H Stoiber - Current Opinion in HIV and AIDS, 2009 - journals.lww.com
Complement, Fc receptors and antibodies: a Trojan horse in H... : Current Opinion in HIV and
AIDS Complement, Fc receptors and antibodies: a Trojan horse in HIV infection? : Current …

A novel trifunctional IgG-like bispecific antibody to inhibit HIV-1 infection and enhance lysis of HIV by targeting activation of complement

L Jia, Y Xu, C Zhang, Y Wang, H Chong, S Qiu, L Wang… - Virology Journal, 2010 - Springer
Background The complement system is not only a key component of innate immunity but
also provides a first line of defense against invading pathogens, especially for viral …