Functional brain networks in the evaluation of patients with neurodegenerative disorders

M Perovnik, T Rus, KA Schindlbeck… - Nature Reviews …, 2023 - nature.com
Network analytical tools are increasingly being applied to brain imaging maps of resting
metabolic activity (PET) or blood oxygenation-dependent signals (functional MRI) to …

The older adult brain is less modular, more integrated, and less efficient at rest: A systematic review of large‐scale resting‐state functional brain networks in aging

HA Deery, R Di Paolo, C Moran, GF Egan… - …, 2023 - Wiley Online Library
The literature on large‐scale resting‐state functional brain networks across the adult
lifespan was systematically reviewed. Studies published between 1986 and July 2021 were …

The default mode network and cognition in Parkinson's disease: A multimodal resting‐state network approach

MC Ruppert, A Greuel, J Freigang… - Human brain …, 2021 - Wiley Online Library
Involvement of the default mode network (DMN) in cognitive symptoms of Parkinson's
disease (PD) has been reported by resting‐state functional MRI (rsfMRI) studies. However …

In vivo human molecular neuroimaging of dopaminergic vulnerability along the Alzheimer's disease phases

A Sala, SP Caminiti, L Presotto, A Pilotto… - Alzheimer's Research & …, 2021 - Springer
Background Preclinical and pathology evidence suggests an involvement of brain dopamine
(DA) circuitry in Alzheimer's disease (AD). We in vivo investigated if, when, and in which …

Brain connectomics: time for a molecular imaging perspective?

A Sala, A Lizarraga, SP Caminiti, VD Calhoun… - Trends in cognitive …, 2023 - cell.com
In the past two decades brain connectomics has evolved into a major concept in
neuroscience. However, the current perspective on brain connectivity and how it underpins …

Identifying the individual metabolic abnormities from a systemic perspective using whole-body PET imaging

T Sun, Z Wang, Y Wu, F Gu, X Li, Y Bai, C Shen… - European Journal of …, 2022 - Springer
Introduction Distinct physiological states arise from complex interactions among the various
organs present in the human body. PET is a non-invasive modality with numerous …

[HTML][HTML] Gender differences in dopaminergic system dysfunction in de novo Parkinson's disease clinical subtypes

C Boccalini, G Carli, A Pilotto, A Padovani… - Neurobiology of …, 2022 - Elsevier
Parkinson's disease (PD) is characterized by heterogeneity in clinical syndromes, prognosis,
and pathophysiology mechanisms. Gender differences in neural anatomy and function are …

Depletion and activation of microglia impact metabolic connectivity of the mouse brain

J Gnörich, A Reifschneider, K Wind, A Zatcepin… - Journal of …, 2023 - Springer
Aim We aimed to investigate the impact of microglial activity and microglial FDG uptake on
metabolic connectivity, since microglial activation states determine FDG–PET alterations …

Single photon emission computed tomography/positron emission tomography molecular imaging for parkinsonism: A fast‐developing field

A Verger, S Grimaldi, MJ Ribeiro… - Annals of …, 2021 - Wiley Online Library
The early differential diagnosis of Parkinson disease and atypical parkinsonism is a major
challenge. The use of single photon emission computed tomography (SPECT)/positron …

Tau biomarkers in dementia: positron emission tomography radiopharmaceuticals in tauopathy assessment and future perspective

M Ricci, A Cimini, R Camedda, A Chiaravalloti… - International Journal of …, 2021 - mdpi.com
Abnormal accumulation of Tau protein is closely associated with neurodegeneration and
cognitive impairment and it is a biomarker of neurodegeneration in the dementia field …