[HTML][HTML] Flaxseed: its bioactive components and their cardiovascular benefits

M Parikh, T Netticadan… - American Journal of …, 2018 - journals.physiology.org
Cardiovascular disease remains the leading cause of mortality and morbidity worldwide.
The inclusion of functional foods and natural health products in the diet are gaining …

Role of oxylipins in cardiovascular diseases

MA Nayeem - Acta Pharmacologica Sinica, 2018 - nature.com
Globally, cardiovascular diseases (CVDs) are the number one cause of mortality.
Approximately 18 million people died from CVDs in 2015, representing more than 30% of all …

Elevated plasma succinate levels are linked to higher cardiovascular disease risk factors in young adults

FJ Osuna-Prieto, B Martinez-Tellez… - Cardiovascular …, 2021 - Springer
Background Succinate is produced by both host and microbiota, with a key role in the
interplay of immunity and metabolism and an emerging role as a biomarker for inflammatory …

Epoxy fatty acids are promising targets for treatment of pain, cardiovascular disease and other indications characterized by mitochondrial dysfunction, endoplasmic …

C McReynolds, C Morisseau, K Wagner… - … lipid signaling pathways, 2020 - Springer
Bioactive lipid mediators resulting from the metabolism of polyunsaturated fatty acids (PUFA)
are controlled by many pathways that regulate the levels of these mediators and maintain …

An overview of the biologic effects of omega-6 oxylipins in humans

GC Shearer, RE Walker - Prostaglandins, Leukotrienes and Essential Fatty …, 2018 - Elsevier
Oxylipins are lipid mediators produced from polyunsaturated fatty acid (PUFA) metabolism,
and are thought to be a molecular explanation for the diverse biological effects of PUFAs …

Dietary modulation of oxylipins in cardiovascular disease and aging

SPB Caligiuri, M Parikh… - American Journal …, 2017 - journals.physiology.org
Oxylipins are a group of fatty acid metabolites generated via oxygenation of polyunsaturated
fatty acids and are involved in processes such as inflammation, immunity, pain, vascular …

[HTML][HTML] Soybean oil lowers circulating cholesterol levels and coronary heart disease risk, and has no effect on markers of inflammation and oxidation

M Messina, G Shearer, K Petersen - Nutrition, 2021 - Elsevier
To reduce risk of coronary heart disease (CHD), replacement of saturated fat (SFA) with
polyunsaturated fat (PUFA) is recommended. Strong and concordant evidence supports this …

Regulatory lipid vicinal diols counteract the biological activity of epoxy fatty acids and can act as biomarkers and mechanisms for disease progression

C McReynolds, B Hammock, C Morisseau - Pharmacology & Therapeutics, 2023 - Elsevier
Polyunsaturated fatty acids (PUFAs) are essential fatty acids required for human health and
are obtained primarily from food or synthesized in the body by highly regulated processes …

Non-targeted metabolomic profiling of coronary heart disease patients with Taohong Siwu decoction treatment

T Tao, T He, H Mao, X Wu, X Liu - Frontiers in Pharmacology, 2020 - frontiersin.org
Traditional Chinese medicine is one of the complementary and alternative therapies to
improve the prognosis of coronary heart disease (CHD). Taohong Siwu Decoction …

Effects of dietary supplementation of fish oil plus vitamin D 3 on gut microbiota and fecal metabolites, and their correlation with nonalcoholic fatty liver disease risk …

X Li, C Pan, W Ma, T Yang, C Wang, W Han… - Food & Function, 2024 - pubs.rsc.org
We previously reported that fish oil plus vitamin D3 (FO+ D) could ameliorate nonalcoholic
fatty liver disease (NAFLD). However, it is unclear whether the beneficial effects of FO+ D on …