Intravenous immunoglobulin therapy: how does IgG modulate the immune system?
I Schwab, F Nimmerjahn - Nature Reviews Immunology, 2013 - nature.com
Intravenous immunoglobulin (IVIG) preparations comprise pooled IgG antibodies from the
serum of thousands of donors and were initially used as an IgG replacement therapy in …
serum of thousands of donors and were initially used as an IgG replacement therapy in …
Paraneoplastic syndromes: an approach to diagnosis and treatment
LC Pelosof, DE Gerber - Mayo Clinic Proceedings, 2010 - Elsevier
Recent medical advances have improved the understanding, diagnosis, and treatment of
paraneoplastic syndromes. These disorders arise from tumor secretion of hormones …
paraneoplastic syndromes. These disorders arise from tumor secretion of hormones …
Intravenous immune globulin in autoimmune and inflammatory diseases
EW Gelfand - New England Journal of Medicine, 2012 - Mass Medical Soc
Intravenous Immune Globulin in Autoimmune and Inflammatory Diseases | New England Journal
of Medicine Skip to main content The New England Journal of Medicine homepage Advanced …
of Medicine Skip to main content The New England Journal of Medicine homepage Advanced …
Anti-inflammatory actions of intravenous immunoglobulin
F Nimmerjahn, JV Ravetch - Annu. Rev. Immunol., 2008 - annualreviews.org
The remarkable success story of the therapeutic application of pooled immunoglobulin G
(IgG) preparations from thousands of donors, the so-called intravenous IgG (IVIG) therapy, to …
(IgG) preparations from thousands of donors, the so-called intravenous IgG (IVIG) therapy, to …
Inhibition of maturation and function of dendritic cells by intravenous immunoglobulin
J Bayry, S Lacroix-Desmazes… - Blood, The Journal …, 2003 - ashpublications.org
Normal immunoglobulin G for therapeutic use (intravenous immunoglobulin [IVIg]) is used in
an increasing number of immune-mediated conditions, including acute and …
an increasing number of immune-mediated conditions, including acute and …
High-dose intravenous immunoglobulins in the treatment of severe acute viral pneumonia: the known mechanisms and clinical effects
X Liu, W Cao, T Li - Frontiers in immunology, 2020 - frontiersin.org
The current outbreak of viral pneumonia, caused by novel coronavirus SARS-CoV-2, is the
focus of worldwide attention. The WHO declared the COVID-19 outbreak a pandemic event …
focus of worldwide attention. The WHO declared the COVID-19 outbreak a pandemic event …
Apoptosis in the anucleate platelet
V Leytin - Blood reviews, 2012 - Elsevier
For many years, programmed cell death, known as apoptosis, was attributed exclusively to
nucleated cells. Currently, however, apoptosis is also well-documented in anucleate …
nucleated cells. Currently, however, apoptosis is also well-documented in anucleate …
Immunomodulation by IVIg and the role of Fc-gamma receptors: classic mechanisms of action after all?
SQ Nagelkerke, TW Kuijpers - Frontiers in immunology, 2015 - frontiersin.org
Intravenous IgG (IVIg) contains polyclonal immunoglobulin G (IgG) from thousands of
donors. It is administered at a low dose at regular intervals as antibody replacement therapy …
donors. It is administered at a low dose at regular intervals as antibody replacement therapy …
A murine model of severe immune thrombocytopenia is induced by antibody- and CD8+ T cell–mediated responses that are differentially sensitive to therapy
L Chow, R Aslam, ER Speck, M Kim… - Blood, The Journal …, 2010 - ashpublications.org
Immune thrombocytopenia (ITP) is a bleeding disorder characterized by antibody-opsonized
platelets being prematurely destroyed in the spleen, although some patients with ITP may …
platelets being prematurely destroyed in the spleen, although some patients with ITP may …
Platelet homeostasis is regulated by platelet expression of CD47 under normal conditions and in passive immune thrombocytopenia
M Olsson, P Bruhns, WA Frazier, JV Ravetch… - Blood, 2005 - ashpublications.org
Interaction between target cell CD47 and the inhibitory macrophage receptor signal
regulatory protein α (SIRPα) counteracts macrophage phagocytosis of CD47-expressing …
regulatory protein α (SIRPα) counteracts macrophage phagocytosis of CD47-expressing …