(250 words): A diverse group of natural biological compounds bind to microtubules and
suppress microtubule dynamics. Here we review the mechanism of microtubule assembly …

Over the past year or so, there have been a number of advances regarding the structure and
assembly of microtubules. Examples are kinesin-decorated microtubules (akin to decorated …

Substoichiometric binding of taxol to tubulin in microtubules potently suppresses
microtubule dynamics, which appears to be the most sensitive antiproliferative mechanism …

Kinesin-1 is a nanoscale molecular motor that walks towards the fast-growing (plus) ends of
microtubules, hauling molecular cargo to specific reaction sites in cells. Kinesin-driven …

Evidence that 13 or 14 contiguous tubulin-GTP subunits are sufficient to cap and stabilize a
microtubule end and that loss of only one of these subunits results in the transition to rapid …

We have characterized the effects of vinblastine on the growing and shortening dynamics at
opposite ends of individual bovine brain microtubules at steady state in vitro by video …

Experiments performed on a cell line (A498) derived from a human kidney carcinoma
revealed non-centrosomal microtubules in the peripheral lamella of many cells. These short …

In the kinesin family, all the molecular motors that have been implicated in the regulation of
microtubule dynamics have been shown to stimulate microtubule depolymerization. Here …

The major microtubule-associated protein in echinoderms is a 77-kDa, WD repeat protein,
called EMAP. EMAP-related proteins have been identified in sea urchins, starfish …

Mitotic movements of chromosomes are usually coupled to the elongation and shortening of
the microtubules to which they are bound. The lengths of kinetochore-associated …