[HTML][HTML] Genetics and molecular pathogenesis of gastric adenocarcinoma

P Tan, KG Yeoh - Gastroenterology, 2015 - Elsevier
Gastric cancer (GC) is globally the fifth most common cancer and third leading cause of
cancer death. A complex disease arising from the interaction of environmental and host …

[HTML][HTML] MiRNA as potential biomarkers and therapeutic targets for gastric cancer

VY Shin, KM Chu - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Gastric cancer is one of the leading causes of cancer mortality in the world. Aberrant
expression of microRNAs (miRNAs) is the hallmark of this disease. MiRNAs are …

Neoplastic reprogramming of patient-derived adipose stem cells by prostate cancer cell-associated exosomes

ZY Abd Elmageed, Y Yang, R Thomas, M Ranjan… - Stem …, 2014 - academic.oup.com
Emerging evidence suggests that mesenchymal stem cells (MSCs) are often recruited to
tumor sites but their functional significance in tumor growth and disease progression …

Discovery of multi-dimensional modules by integrative analysis of cancer genomic data

S Zhang, CC Liu, W Li, H Shen, PW Laird… - Nucleic acids …, 2012 - academic.oup.com
Recent technology has made it possible to simultaneously perform multi-platform genomic
profiling (eg DNA methylation (DM) and gene expression (GE)) of biological samples …

MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension: results of a network bioinformatics approach

VN Parikh, RC Jin, S Rabello, N Gulbahce, K White… - Circulation, 2012 - Am Heart Assoc
Background—Pulmonary hypertension (PH) is driven by diverse pathogenic etiologies.
Owing to their pleiotropic actions, microRNA molecules are potential candidates for …

MicroRNA dysregulation in gastric cancer: a new player enters the game

WKK Wu, CW Lee, CH Cho, D Fan, K Wu, J Yu… - Oncogene, 2010 - nature.com
Gastric carcinogenesis is a multistep process involving genetic and epigenetic alteration of
protein-coding proto-oncogenes and tumor-suppressor genes. Recent discoveries have …

Circulating miR-15b and miR-130b in serum as potential markers for detecting hepatocellular carcinoma: a retrospective cohort study

AM Liu, TJ Yao, W Wang, KF Wong, NP Lee, ST Fan… - BMJ open, 2012 - bmjopen.bmj.com
Objective Serum α-fetoprotein (AFP) is the most commonly used biomarker for screening
hepatocellular carcinoma (HCC) but fails to detect about half of the patients. Thus, we …

Advances in molecular biomarkers for gastric cancer: miRNAs as emerging novel cancer markers

HH Wu, W Lin, KW Tsai - Expert reviews in molecular medicine, 2014 - cambridge.org
Carcinoma of the stomach is one of the most prevalent cancer types in the world. Although
the incidence of gastric cancer is declining, the outcomes of gastric cancer patients remain …

The miR-217 microRNA functions as a potential tumor suppressor in pancreatic ductal adenocarcinoma by targeting KRAS

WG Zhao, SN Yu, ZH Lu, YH Ma, YM Gu… - …, 2010 - academic.oup.com
Aberrantly expressed microRNA (miRNA) is frequently associated with a variety of cancers,
including pancreatic ductal adenocarcinoma (PDAC). In this study, we investigated the …

MicroRNAs in pathogenesis, diagnosis, and treatment of gastroesophageal cancers

JH Song, SJ Meltzer - Gastroenterology, 2012 - Elsevier
The incidence of gastroesophageal cancers is increasing each year, but despite much
research, their molecular mechanisms are incompletely understood. microRNAs (miRNAs) …