From early embryonic development to adulthood, GABA release participates in the
construction of the mammalian cerebral cortex. The maturation of GABAergic …

Here, we review the stem cell hallmarks of endogenous neural stem cells (NSCs) during
development and in some niches of the adult mammalian brain to then compare these with …

INTRODUCTION Inhibitory interneurons balance the excitation and inhibition of neural
networks and therefore are key to normal brain function. In the developing brain, young …

The importance of neuronal morphology in brain function has been recognized for over a
century. The broad applicability of" digital reconstructions" of neuron morphology across …

In the forebrain, cortical structures consist of networks of excitatory and inhibitory neurons
born in distant locations. Understanding how these two major classes of neurons integrate …

Neurogenic regions of mammalian brain produce many more neurons that will eventually
survive and reach a mature stage. Developmental cell death affects both embryonically …

Caspases are intimately associated with altering various signaling pathways, resulting in
programmed cell death or apoptosis. Apoptosis is necessary for the normal homeostasis of …

Throughout early phases of brain development, the two main neural signaling mechanisms—
excitation and inhibition—are dynamically sculpted in the neocortex to establish primary …

Two decades after the discovery that neural stem cells (NSCs) populate some regions of the
mammalian central nervous system (CNS), deep knowledge has been accumulated on their …

Severe infections during pregnancy are one of the major risk factors for cognitive impairment
in the offspring. It has been suggested that maternal inflammation leads to dysfunction of …