The search for translational pain outcomes to refine analgesic development: Where did we come from and where are we going?

R González-Cano, Á Montilla-García… - Neuroscience & …, 2020 - Elsevier
Pain measures traditionally used in rodents record mere reflexes evoked by sensory stimuli;
the results thus may not fully reflect the human pain phenotype. Alterations in physical and …

[HTML][HTML] Exploring natural products-based cancer therapeutics derived from egyptian flora

HR El-Seedi, N Yosri, SAM Khalifa, Z Guo… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological Relevance Egyptian plants are a rich source of natural
molecules, representing considerable biodiversity due to climate variations between the …

Investigation of the anti-inflammatory effects of stigmasterol in mice: insight into its mechanism of action

LV Morgan, F Petry, M Scatolin… - Behavioural …, 2021 - journals.lww.com
Stigmasterol is a phytosterol that presents pharmacologic properties. However, its anti-
inflammatory mechanism and antinociceptive effect are not yet elucidated. Thus, the present …

Anti‐Inflammatory and Antimicrobial Effects of Eucalyptus spp. Essential Oils: A Potential Valuable Use for an Industry Byproduct

ES Salvatori, LV Morgan, S Ferrarini… - Evidence‐Based …, 2023 - Wiley Online Library
In Brazil, the use of Eucalyptus is focused on the production of wood or pulp for the paper
industry but without any general recovery of waste, with leaves and branches being left on …

Antioxidant activity, antibacterial and inhibitory effect of intestinal disaccharidases of extracts obtained from Eugenia uniflora L. Seeds

J Lazzarotto-Figueiró, AP Capelezzo… - Brazilian Journal of …, 2020 - SciELO Brasil
The use of medicinal plants for disease prevention, treatment and cure is an ancient practice
used by humanity, and many plants species are used in bioprospecting research. In this …

Assessment of acute toxicity, genotoxicity, and anti-inflammatory activity of SteLL, a lectin from Schinus terebinthifolia Raddi. Leaves, in mice

A de Oliveira Marinho, JA da Costa… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacology relevance Schinus terebinthifolia Raddi (Anacardiaceae),
known as Brazilian pepper tree, stands out as a medicinal plant widely used in traditional …

Curcumin and n-acetylcysteine cocrystal produced with supercritical solvent: characterization, solubility, and preclinical evaluation of antinociceptive and anti …

AR Paulazzi, BO Alves, GAL Zilli, AE Dos Santos… - …, 2022 - Springer
Curcumin presents a promising anti-inflammatory potential, but its low water-solubility and
bioavailability hinder its application. In this sense, cocrystallization represents a tool for …

Anti-inflammatory and anti-nociceptive property of Capparis tomentosa Lam. root extracts

GH Tekulu, T Hiluf, H Brhanu, EM Araya, H Bitew… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance Capparis tomentosa Lam. root is one of the
commonly used traditional medicines for the treatment of pain and inflammatory conditions …

Beta-sitosterol and its antinociceptive mechanism action

AA Şakul, ME Okur - Journal of Faculty of Pharmacy of Ankara …, 2021 - dergipark.org.tr
Objective: In this study, the possible central antinociceptive activity of beta-sitosterol is
investigated along with its association of stimulation of opioidergic, serotonergic, adrenergic …

Ethnopharmacological and botanical evaluation of medicinal plants used by Brazilian Amazon Indian community

AZ Meneguelli, EES Camargo, DF Buccini… - Interações (Campo …, 2020 - SciELO Brasil
Plants have been widely used to treat many diseases, especially by traditional communities
as Indians, that can be considered as an important source of empirical knowledge about the …