Twenty-five years of clinical applications using adaptive optics ophthalmoscopy

JIW Morgan, TYP Chui, K Grieve - Biomedical Optics Express, 2022 - opg.optica.org
Twenty-five years ago, adaptive optics (AO) was combined with fundus photography,
thereby initiating a new era in the field of ophthalmic imaging. Since that time, clinical …

Applications of Adaptive Optics Imaging for Studying Conditions Affecting the Fovea

J Kreis, J Carroll - Annual Review of Vision Science, 2024 - annualreviews.org
The fovea is a highly specialized region of the central retina, defined by an absence of inner
retinal layers and the accompanying vasculature, an increased density of cone …

[HTML][HTML] Histologic cell shape descriptors for the retinal pigment epithelium in age-related macular degeneration: A comparison to unaffected eyes

L von der Emde, M Vaisband… - … Vision Science & …, 2022 - iovs.arvojournals.org
Purpose: Phenotype alterations of the retinal pigment epithelium (RPE) are a main
characteristic of age-related macular degeneration (AMD). Individual RPE cell shape …

Strip-based digital image registration for distortion minimization and robust eye motion measurement from scanned ophthalmic imaging systems

M Zhang, E Gofas-Salas, BT Leonard, Y Rui… - Biomedical Optics …, 2021 - opg.optica.org
Retinal image-based eye motion measurement from scanned ophthalmic imaging systems,
such as scanning laser ophthalmoscopy, has allowed for precise real-time eye tracking at …

Human foveal cone and RPE cell topographies and their correspondence with foveal shape

RC Baraas, HR Pedersen… - … & Visual Science, 2022 - iovs.arvojournals.org
Purpose: To characterize the association between foveal shape and cone and retinal
pigment epithelium (RPE) cell topographies in healthy humans. Methods: Multimodal …

High-resolution adaptive optics-trans-scleral flood illumination (AO-TFI) imaging of retinal pigment epithelium (RPE) in central serous chorioretinopathy (CSCR)

V Govindahari, R Dornier, S Ferdowsi, C Moser… - Scientific Reports, 2024 - nature.com
This study aims to correlate adaptive optics-transscleral flood illumination (AO-TFI) images
of the retinal pigment epithelium (RPE) in central serous chorioretinopathy (CSCR) with …

Multi-spectral autofluorescence variability of the individual retinal pigmented epithelial cells in healthy aging eyes

DMW Lee, M Zhang, VC Snyder, EA Rossi - Scientific Reports, 2024 - nature.com
The retinal pigment epithelium (RPE) is vital for the healthy function of the retina. Cellular
level changes in the RPE are not visualized with current clinical techniques due to a lack of …

Design of a radial multi-offset detection pattern for in vivo phase contrast imaging of the inner retina in humans

E Gofas-Salas, Y Rui, P Mecê, M Zhang… - Biomedical optics …, 2021 - opg.optica.org
Previous work has shown that multi-offset detection in adaptive optics scanning laser
ophthalmoscopy (AOSLO) can be used to image transparent cells such as retinal ganglion …

[HTML][HTML] In vivo retinal pigment epithelium imaging using transscleral optical imaging in healthy eyes

L Kowalczuk, R Dornier, M Kunzi, A Iskandar… - Ophthalmology …, 2023 - Elsevier
Objective To image healthy retinal pigment epithelial (RPE) cells in vivo using Transscleral
OPtical Imaging (TOPI) and to analyze statistics of RPE cell features as a function of age …

Dynamic distortion in resonant galvanometric optical scanners

V Akondi, B Kowalski, SA Burns, A Dubra - Optica, 2020 - opg.optica.org
High-speed optical systems are revolutionizing biomedical imaging in microscopy, DNA
sequencing, and flow cytometry, as well as numerous other applications, including data …