Phytocannabinoids: origins and biosynthesis

T Gülck, BL Møller - Trends in plant science, 2020 - cell.com
Phytocannabinoids are bioactive natural products found in some flowering plants, liverworts,
and fungi that can be beneficial for the treatment of human ailments such as pain, anxiety …

Iridium-catalyzed asymmetric synthesis of functionally rich molecules enabled by (phosphoramidite, olefin) ligands

SL Rossler, DA Petrone… - Accounts of Chemical …, 2019 - ACS Publications
Conspectus The catalytic, asymmetric synthesis of complex molecules has been a core
focus of our research program for some time because developments in the area can have an …

Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C (ut) annabinoid” System

KF Tóth, D Ádám, T Bíró, A Oláh - Molecules, 2019 - mdpi.com
The endocannabinoid system (ECS) has lately been proven to be an important, multifaceted
homeostatic regulator, which influences a wide-variety of physiological processes all over …

A GPCR-based yeast biosensor for biomedical, biotechnological, and point-of-use cannabinoid determination

K Miettinen, N Leelahakorn, A Almeida, Y Zhao… - Nature …, 2022 - nature.com
Eukaryotic cells use G-protein coupled receptors to sense diverse signals, ranging from
chemical compounds to light. Here, we exploit the remarkable sensing capacity of G-protein …

Δ9-cis-Tetrahydrocannabinol: Natural Occurrence, Chirality, and Pharmacology

MA Schafroth, G Mazzoccanti… - Journal of natural …, 2021 - ACS Publications
The cis-stereoisomers of Δ9-THC [(−)-3 and (+)-3] were identified and quantified in a series
of low-THC-containing varieties of Cannabis sativa registered in Europe as fiber hemp and …

Cannabimimetic plants: are they new cannabinoidergic modulators?

A Kumar, M Premoli, F Aria, SA Bonini, G Maccarinelli… - Planta, 2019 - Springer
Abstract Main Conclusion Phytochemicals and secondary metabolites able to interact with
the endocannabinoid system (Cannabimimetics) have been recently described in a broad …

Biosynthesis and synthetic biology of psychoactive natural products

CS Jamieson, J Misa, Y Tang… - Chemical Society Reviews, 2021 - pubs.rsc.org
Psychoactive natural products play an integral role in the modern world. The tremendous
structural complexity displayed by such molecules confers diverse biological activities of …

Synthetic Strategies for Rare Cannabinoids Derived from Cannabis sativa

GN Nguyen, EN Jordan, O Kayser - Journal of natural products, 2022 - ACS Publications
Efficient syntheses of eight key cannabinoids were established and optimized. Predominant
cannabinoids such as cannabigerol (CBG-C5) and cannabidiol (CBD-C5) were prepared …

Natural products from bryophytes: from basic biology to biotechnological applications

A Horn, A Pascal, I Lončarević… - Critical Reviews in …, 2021 - Taylor & Francis
Natural products from plants have served mankind in a wide range of applications, such as
medicines, perfumes, or flavoring agents. For this reason, synthesis, regulation and function …

Bryophytes as a source of bioactive volatile terpenoids–A review

A Ludwiczuk, Y Asakawa - Food and Chemical Toxicology, 2019 - Elsevier
Bryophytes, phylogenetically placed between the algae and pteridophytes, are divided into
three classes: mosses, liverworts, and hornworts. Traditional system of medicine throughout …