Many bacteria can infect and persist inside their hosts for long periods of time. This can be
due to immunosuppression of the host, immune evasion by the pathogen and/or ineffective …

BACKGROUND The escalating crisis of multidrug resistance is raising fears of untreatable
infections caused by bacterial “superbugs.” However, many patients already suffer from …

Bacterial persister cells are phenotypic variants that exhibit a transient non-growing state
and antibiotic tolerance. Here, we provide in vitro evidence of Staphylococcus aureus …

Persisters are transiently tolerant variants that allow populations to avoid eradication by
antibiotic treatment. Their antibiotic tolerance is non-genetic, not inheritable and results from …

Bacteria have evolved numerous means of survival in adverse environments with dormancy,
as represented by “persistence” and the “viable but nonculturable”(VBNC) state, now …

For decades, mankind has dominated the battle against bacteria, yet the tide is slowly
turning. Our antibacterial strategies are becoming less effective, allowing bacteria to get the …

Bacterial persisters are able to tolerate high levels of antibiotics and give rise to new
populations. Persister tolerance is generally attributed to minimally active cellular processes …

Bacterial persisters are phenotypic variants that survive antibiotic treatment in a dormant
state and can be formed by multiple pathways. We recently proposed that the second …

All bacterial populations harbor a small fraction of transiently antibiotic-tolerant cells called
persisters. These phenotypic variants compromise successful antibiotic treatment because …

Persister and viable but non-culturable (VBNC) cells are two clonal subpopulations that can
survive multidrug exposure via a plethora of putative molecular mechanisms. Here, we …