With the emergence of antibiotic resistance, the interest for antimicrobial agents has recently
increased again in public health. Copper was recognized in 2008 by the United States …

Transition metals are required trace elements for all forms of life. Due to their unique
inorganic and redox properties, transition metals serve as cofactors for enzymes and other …

Mycobacterium tuberculosis is a facultative intracellular pathogen that thrives inside host
macrophages. A key trait of M. tuberculosis is to exploit and manipulate metal cation …

Copper (Cu) is an essential trace element for all living organisms and used as cofactor in
key enzymes of important biological processes, such as aerobic respiration or superoxide …

Traces of metal are required for fundamental biochemical processes, such as
photosynthesis and respiration. Cyanobacteria metal homeostasis acquires an important …

Copper is a ubiquitous element in the environment as well as living organisms, with its redox
capabilities and complexation potential making it indispensable for many cellular functions …

Metal ions fulfil a plethora of essential roles within bacterial pathogens. In addition to acting
as necessary cofactors for cellular proteins, making them indispensable for both protein …

Conspectus The human innate immune system has evolved the means to reduce the
bioavailability of first-row late d-block transition metal ions to invading microbial pathogens …

Mycobacteria have a distinctive glycolipid-rich outer membrane, the mycomembrane, which
is a critical target for tuberculosis drug development. However, proteins that associate with …

Tuberculosis is a severe disease affecting millions worldwide. Unfortunately, treatment
strategies are hampered both by the prohibitively long treatment regimen and the rise of …