Glioblastomas are the most common form of malignant primary brain tumor and an important
cause of morbidity and mortality. In recent years there have been important advances in …

The standard of care (SOC) for high-grade gliomas (HGG) is maximally safe surgical
resection, followed by concurrent radiation therapy (RT) and temozolomide (TMZ) for 6 …

Primary CNS tumours refer to a heterogeneous group of tumours arising from cells within the
CNS, and can be benign or malignant. Malignant primary brain tumours remain among the …

Summary The European Association for Neuro-Oncology guideline provides
recommendations for the clinical care of adult patients with astrocytic and oligodendroglial …

The NCCN Guidelines for Central Nervous System (CNS) Cancers focus on management of
adult CNS cancers ranging from noninvasive and surgically curable pilocytic astrocytomas …

Glioblastoma is an aggressive and inevitably recurrent primary intra-axial brain tumor with a
dismal prognosis. The current mainstay of treatment involves maximally safe surgical …

Background The role of temozolomide chemotherapy in newly diagnosed 1p/19q non-co-
deleted anaplastic gliomas, which are associated with lower sensitivity to chemotherapy and …

Glioblastoma (GBM) is the most common primary malignant brain tumor in adults.
Regardless of ideal multidisciplinary treatment, including maximal surgical resection …

PURPOSE Despite intensive treatment with surgery, radiation therapy, temozolomide (TMZ)
chemotherapy, and tumor-treating fields, mortality of newly diagnosed glioblastoma (nGBM) …

Glioblastoma is the most aggressive primary brain tumor with a poor prognosis. The 2021
WHO CNS5 classification has further stressed the importance of molecular signatures in …